“…Orthopedic surgeries are frequently associated with different outcomes in other types of surgery. Due to copious amounts of bone destruction and soft tissue injury, orthopedic surgery is generally associated with insufferable post-surgical pain [ 62 ]. Second, one study found that musical interventions performed immediately after TKR obviously alleviated pain over time [ 43 ] and mentioned that such interventions resulted in reduced opioid dosages and incidence of adverse reactions.…”
Background
A growing number of patients continue to receive total knee replacement (TKR) surgery. Nevertheless, such surgeries result in moderate to severe postoperative pain and difficulty in managing it. Musical interventions are regarded as a type of multimodal analgesia, achieving beneficial results in other clinical treatments. This study aims to evaluate the effect of musical interventions in improving short-term pain outcomes following TKR in order to determine a more reasonable and standard way of delivering musical intervention.
Methods
A systematic search was conducted to identify available and relevant randomized controlled trials (RCTs) regarding musical interventions compared against non-musical interventions in patients treated with TKR in Embase, MEDLINE, Cochrane Library, Web of Science, CNKI, and Wanfang Med Online up to 8 January 2020. The authors independently assessed study eligibility and risk of bias and collected the outcomes of interest to analyze. The statistical analysis was conducted using the Review Manager (RevMan) version 5.30 software.
Results
Eight RCTs comprised of 555 patients satisfied the inclusion criteria and were enrolled in the present study. The results showed no significant difference between the music and control groups in pain of the visual analog scale (VAS), during postoperative recovery room, back to the ward after surgery; anxiety degree of VAS; heart rate; respiratory rate; oxygen saturation; blood pressure, systolic blood pressure, and diastolic blood pressure. Nevertheless, significant differences were observed between the two groups in average increase in continuous passive motion (CPM) angles and LF/HF ratio (one kind index of heart rate variability).
Conclusions
Musical interventions fail to demonstrate an obvious effect in improving short-term pain outcomes following TKR. A reasonable standardization of musical interventions, including musical type, outcome measures used, outcomes measured, duration, timing and headphones or players, may improve pain outcomes with certain advantages and should be further explored after TKR.
“…Orthopedic surgeries are frequently associated with different outcomes in other types of surgery. Due to copious amounts of bone destruction and soft tissue injury, orthopedic surgery is generally associated with insufferable post-surgical pain [ 62 ]. Second, one study found that musical interventions performed immediately after TKR obviously alleviated pain over time [ 43 ] and mentioned that such interventions resulted in reduced opioid dosages and incidence of adverse reactions.…”
Background
A growing number of patients continue to receive total knee replacement (TKR) surgery. Nevertheless, such surgeries result in moderate to severe postoperative pain and difficulty in managing it. Musical interventions are regarded as a type of multimodal analgesia, achieving beneficial results in other clinical treatments. This study aims to evaluate the effect of musical interventions in improving short-term pain outcomes following TKR in order to determine a more reasonable and standard way of delivering musical intervention.
Methods
A systematic search was conducted to identify available and relevant randomized controlled trials (RCTs) regarding musical interventions compared against non-musical interventions in patients treated with TKR in Embase, MEDLINE, Cochrane Library, Web of Science, CNKI, and Wanfang Med Online up to 8 January 2020. The authors independently assessed study eligibility and risk of bias and collected the outcomes of interest to analyze. The statistical analysis was conducted using the Review Manager (RevMan) version 5.30 software.
Results
Eight RCTs comprised of 555 patients satisfied the inclusion criteria and were enrolled in the present study. The results showed no significant difference between the music and control groups in pain of the visual analog scale (VAS), during postoperative recovery room, back to the ward after surgery; anxiety degree of VAS; heart rate; respiratory rate; oxygen saturation; blood pressure, systolic blood pressure, and diastolic blood pressure. Nevertheless, significant differences were observed between the two groups in average increase in continuous passive motion (CPM) angles and LF/HF ratio (one kind index of heart rate variability).
Conclusions
Musical interventions fail to demonstrate an obvious effect in improving short-term pain outcomes following TKR. A reasonable standardization of musical interventions, including musical type, outcome measures used, outcomes measured, duration, timing and headphones or players, may improve pain outcomes with certain advantages and should be further explored after TKR.
“…1,2 The surgical procedure involves extensive bone resection (of both the distal femur and proximal tibia) as well as soft tissue excision and is frequently associated with moderate to severe postoperative pain. 3 Inadequate perioperative pain control may hinder early rehabilitation and prolong hospitalization, and is also a strong predictor of persistent pain beyond 3 months. 4 Adequate analgesia after TKA is therefore considered paramount to facilitate effective rehabilitation and timely hospital discharge.…”
Section: Resultsmentioning
confidence: 99%
“…showed a favorable analgesic profile as evidenced by 3 positive secondary outcomes. These positive outcomes were lower pain scores 12 hours postoperatively both at rest (4 [2-6.3], 4 [2.3-6], and 3 [1][2][3][4]; P = 0.007) and on movement (6 [4][5][6][7][8], 6 [3][4][5][6][7][8], and 4 [2][3][4][5][6]; P = 0.002), a lower incidence of "rescue" intravenous patient-controlled analgesia (42%, 34%, and 20%; P = 0.031), and the lowest cumulative opioid requirements for the first 48 hours postoperatively (86 ± 71, 68 ± 46, and 59 ± 39; P < 0.005, group 3 compared with group 1).…”
“…[ 1 , 2 ] However, severe pain is an important clinical challenge after total knee replacement, due to the soft tissue injury and a large amount of bone destruction involved. [ 3 ] At present, different regional analgesia techniques, which include peripheral nerve block, epidural anesthesia, and local infiltration analgesia, [ 4 – 6 ] cannot provide sufficient analgesia, so that additional opioids were taken to control the pain. However, the use of opioids could lead to some side effects such as headaches, urinary retention and so on that the clinical application of the drug is limited.…”
Background:
Total knee arthroplasty (TKA) is gradually emerging as the treatment of choice for end-stage osteoarthritis. In the past, intravenous (IV) versus oral acetaminophen (APAP) treatment is still a controversial subject in TKA. Therefore, we write this systematic review and meta-analysis to evaluate the efficacy of IV versus oral APAP on pain and recovery after TKA.
Methods:
Embase, Pubmed, and Cochrane Library were comprehensively searched. Randomized controlled trials, cohort studies were included in our meta-analysis. Five studies that compared IV APAP groups with oral APAP groups were included in our meta-analysis. The research was reported according to the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines to ensure the reliability and verity of results.
Results:
Pooled results indicated that no significant difference between the IV APAP groups and oral APAP groups in term of VAS score at 24 hours (
P
= .67), 48 hours (
P
= 0.08), and total morphine consumption at 24 hours (
P
= .07), but there was a significant difference in terms of length of hospital stay (LOS) (
P
= .0004).
Conclusion:
IV APAP was not found to be superior to oral APAP in patients undergoing TKA in terms of VAS scores at 24 hours, 48 hours, and total morphine consumption at 24 hours. However, it can significantly reduce the LOS. We still need a large of high-quality research to verify the relationship between the oral and the IV APAP to give the conclusion.
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