2014
DOI: 10.5114/pwki.2014.45146
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Abstract: IntroductionCongenital left ventricular to right atrial (LV-RA) shunt (Gerbode defect) is rare, while acquired LV-RA shunt has been increasingly reported. As yet, systematically incorporated data of the LV-RA shunt have not been presented.AimTo present the clinical features, diagnostic challenge and management strategies of congenital and acquired LV-RA shunts.Material and methodsThe data source was based on a comprehensive literature retrieval of the LV-RA shunt in the period 1990–2013.ResultsIn comparison wi… Show more

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Cited by 23 publications
(39 citation statements)
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References 95 publications
(39 reference statements)
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“…The presence of normal diastolic pulmonary arterial pressure using pulmonic regurgitation jet is also very useful to distinguish the true pulmonary arterial hypertension from high velocity jet in the RA caused by Gerbode defect[ 4 , 5 ]. Actually, only about 2/3 of the LV-RA shunts of either congenital or acquired origin can be well diagnosed with TTE[ 6 ]. The 1/3 of others have to rely on other means like contrast echo, TEE, MRI, CTA or catheterization for accurate diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…The presence of normal diastolic pulmonary arterial pressure using pulmonic regurgitation jet is also very useful to distinguish the true pulmonary arterial hypertension from high velocity jet in the RA caused by Gerbode defect[ 4 , 5 ]. Actually, only about 2/3 of the LV-RA shunts of either congenital or acquired origin can be well diagnosed with TTE[ 6 ]. The 1/3 of others have to rely on other means like contrast echo, TEE, MRI, CTA or catheterization for accurate diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…In a recent large review of LV-RA shunts, 121 patients were identified in the literature; of those patients, 88 had acquired defects. 12 The etiologies of those acquired defects were postoperative (59%), infectious (28%), ischemic (5.7%), iatrogenic (4.5%), and traumatic (2.3%). Of the postoperative patients, 39 had valve surgery and 13 had surgery for congenital heart disease, five procedures of which were VSD repair.…”
Section: Discussionmentioning
confidence: 99%
“…In a review of acquired Gerbode defects published from 1990 to 2013 [2], 59% were post-operative with 75% of these occurring post-heart valve surgery. If hemodynamically significant, they result in volume loading of both ventricles and may lead to heart failure.…”
Section: To the Editormentioning
confidence: 99%