1939
DOI: 10.1042/bj0330090
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Experiments on the metabolism of glycine

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Cited by 26 publications
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“…One possibility may be that the biosynthesis of urea in the liver in these cases is accomplished not by the ornithine cycle, but by another, normally little used. For example, Bach (1939) has presented some evidence that glutamic acid could take up ammonia to form glutamine which can combine with a further molecule of ammonia and carbon dioxide to yield glutamic acid and urea. Whether this is correct or not, it is not impossible that other cycles for urea synthesis exist in the body.…”
Section: Discussionmentioning
confidence: 99%
“…One possibility may be that the biosynthesis of urea in the liver in these cases is accomplished not by the ornithine cycle, but by another, normally little used. For example, Bach (1939) has presented some evidence that glutamic acid could take up ammonia to form glutamine which can combine with a further molecule of ammonia and carbon dioxide to yield glutamic acid and urea. Whether this is correct or not, it is not impossible that other cycles for urea synthesis exist in the body.…”
Section: Discussionmentioning
confidence: 99%