Experimental Use of N-Butyl Cyanoacrylate Tissue Adhesive on Lung Parenchyma after Pulmonary Resection

Çağırıcı, Ufuk; Çetin, Yaser Said; Çakan, Alpaslan; Samancılar, Özgür; Veral, Alı; Aşkar, Fatma Zekiye

doi:10.1055/s-2006-924579

Cited by 14 publications

(10 citation statements)

References 7 publications

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“…Biological glues and adhesives (Histoacryl, Bioglue, Floseal, Tisseel) based on cyanoacrylates192–198 or fibrin198, 199 have been used for some time in reconstructive surgery of soft connective tissues. These have been used in thoracic aortic repair,196, 199 abdominal surgery,192 corneal perforations,194 nerve,198 lung,197 plastic surgery193, 195, 200 and otology 201. Most recently they have also been applied in tension and weight‐bearing connective tissues such as the meniscus to reattach bucket handle tears202, 203 and in the fixation of talar osteochondral fractures 204.…”

Section: Integration Of Bioscaffold Constructs Into Cartilaginous Defmentioning

confidence: 99%

Accumulation and toxicity of metals (copper, zinc, cadmium, and lead) and organic compounds (geraniol and benzo[a]pyrene) in the oribatid miteOppia nitens

Owojori

Siciliano

2012

Enviro Toxic and Chemistry

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The oribatid mite Oppia nitens has been suggested as a test species for ecotoxicological assessment of contaminated boreal soils. Knowledge of the ecotoxicity of pollutants of different modes of action to this species is necessary to assess its relative sensitivity in comparison with other invertebrates. The toxicity of four metals and two organic chemicals to O. nitens was evaluated over a 28- or 35-d period. Mite survival, reproduction, and tissue accumulation were assessed at the end of the test. Reproduction was a more sensitive endpoint than survival for all of the compounds except geraniol. The reproduction median inhibitory concentration (IC50) values for Cu, Zn, Cd, and Pb were 2,896, 1,562, 137, and 1,678 mg/kg, respectively, whereas those for benzo[a]pyrene and geraniol were greater than 1,600 and 283 mg/kg. The median lethal concentration (LC50) values for Cu, Zn, Cd, and Pb were 3,311, 2,291, 603, and 6,761 mg/kg, respectively, whereas those for benzo[a]pyrene and geraniol were greater than 1,600 and 251 mg/kg. When effects on reproduction are compared with those of other soil invertebrates, O. nitens appears less sensitive to Cu and Zn but within the same order of magnitude of sensitivity as that for Cd and Pb. Despite its lower sensitivity to Cu and Zn, O. nitens is a member of a group underrepresented in ecotoxicological evaluations and should therefore be included in test battery for risk assessment of contaminated boreal and other northern soils.

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Section: Integration Of Bioscaffold Constructs Into Cartilaginous Defmentioning

confidence: 99%

Accumulation and toxicity of metals (copper, zinc, cadmium, and lead) and organic compounds (geraniol and benzo[a]pyrene) in the oribatid miteOppia nitens

Owojori

Siciliano

2012

Enviro Toxic and Chemistry

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“…In addition postoperative air leakage may cause serious complications, such as pleural empyema, nosocomial pneumonia, or prolonged need for chest tube and hospitalisation [1,2]. Recently, some new synthetic sealants were developed and experimentally evaluated using animal models [1,[3][4][5][6][7][8][9][10][11][12]. The aim of this experimental study was to evaluate the effectiveness of N-butyl…”

Section: Introductionmentioning

confidence: 99%

The Experimental Use of N-Butyl Cyanoacrylate Tissue Adhesive in Pulmonary Wedge Resections

Koşar

Kapıcıbaşı

Alpay

et al. 2012

Heart, Lung and Circulation

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“…More commonly, surgical procedures have utilized cyanoacrylates as tissue adhesives [6] as well as substrate for vascular embolic procedures [7]. The medical formulations include the least toxic forms (typically n-butyl cyanoacrylate and other types).…”

Section: Discussionmentioning

confidence: 99%

Acute Lymphoblastic Leukemia in a Patient with Chronic Cyanoacrylate Exposure

Layden

Joseph²,

Tallman³

et al. 2007

Acta Haematol

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Environmental agents have long been thought to be linked to the development of malignancies. Due to the difficulty in identifying and verifying exposures to such agents, only a few chemical compounds are clearly linked to malignancies. We report here the case of a 36-year-old man with pre-B cell acute lymphoblastic leukemia. This patient was using industrial strength glue to reattach a chipped tooth for approximately 1 year, and such use was associated with chronic exposure of his oral mucosa to this glue. This case raises the possibility that chronic exposure to cyanoacrylates, the adhesive agents in industrial strength glue, may be associated with the development of acute lymphoblastic leukemia in humans.

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Experimental Use of N-Butyl Cyanoacrylate Tissue Adhesive on Lung Parenchyma after Pulmonary Resection

Abstract: N-butyl cyanoacrylate was effective in preventing air leak from the pulmonary resection surface even with high airway pressure levels. It could be used as an aid for pulmonary resection lines or to control the air leak from pulmonary parenchyma.

Cited by 14 publications

References 7 publications

Accumulation and toxicity of metals (copper, zinc, cadmium, and lead) and organic compounds (geraniol and benzo[a]pyrene) in the oribatid miteOppia nitens

Accumulation and toxicity of metals (copper, zinc, cadmium, and lead) and organic compounds (geraniol and benzo[a]pyrene) in the oribatid miteOppia nitens

The Experimental Use of N-Butyl Cyanoacrylate Tissue Adhesive in Pulmonary Wedge Resections

Acute Lymphoblastic Leukemia in a Patient with Chronic Cyanoacrylate Exposure

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