“…With the need to replace refrigerants, it is essential to identify the heat transfer coefficient, void fraction and pressure drop in the two-phase flow of boiling and condensation, since the predictions of these values are indispensable for the optimization of refrigeration cycle components (Greco, 2008). For this reason, in the last eight years, heat transfer coefficient and pressure drop (Anwar et al, 2015;Choi et al, 2014;Del Col et al, 2013;Del Col et al, 2010;Illán-Gómez et al, 2015;Li et al, 2012;Lu et al, 2013;Mortada et al, 2012;Padilla et al, 2011;Saitoh et al, 2011;Sempértegui-Tapia and Ribatski, 2017a, b;Wang et al, 2012) and critical heat flux (Mastrullo et al, 2016;Mastrullo et al, 2017) have been evaluated under conditions of two-phase flow in smooth tubes. Most of the above-mentioned papers deal with mini and microchannels (internal diameter < 3mm, according to Kandlikar and Grande (2003)), which are typical in automotive air conditioning system applications.…”