Experimental Trypanosoma evansi infection in South American coati (Nasua nasua): hematological, biochemical and histopathological changes

Herrera, Heitor Miraglia; Alessi, Antônio Carlos; Marques, Luiz Carlos; Santana, Áureo Evangelista; Aquino, Lúcia Padilha Cury Thomaz de; Menezes, Renato; Moraes, Marcela Barbosa de; Machado, Ricardo

doi:10.1016/s0001-706x(01)00204-2

Cited by 43 publications

(38 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A anemia é a característica mais comum em infecções por tripanossomas e já foi descrita em ovelhas, cabras, cães, coatis (Nasua nasua), camelos e búfalos (ONAH et al, 1996;SHARMA et al, 2000;AQUINO et al, 2002, HERRERA et al, 2002ATARHOUCH et al, 2003;HILALI et al, 2006). As médias do VCM e da CHCM não variaram entre os grupos de animais infectados e não infectados, caracterizando uma anemia normocítica normocrômica.…”

Section: Resultsunclassified

Resposta eritropoética de ratos em diferentes graus de parasitemia por Trypanosoma evansi

et al. 2007

View full text Add to dashboard Cite

show abstract

Section: Resultsunclassified

Resposta eritropoética de ratos em diferentes graus de parasitemia por Trypanosoma evansi

et al. 2007

View full text Add to dashboard Cite

show abstract

“…In this area, trypanosomiasis due to Trypanosoma evansi is enzootic since it affects many species of domestic and wild animals (Franke et al, 1994;Herrera et al, 2002). The course of the disease lasts between one week to six months (Woo, 1977) and usually results in emaciation and death.…”

Section: Introductionmentioning

confidence: 99%

“…Anemia is a commonly found in horses, donkeys, dogs and coatis (Nasua nasua) experimentally infected with T. evansi (Marques et al, 2000;Soodan et al, 1996;Aquino et al, 2002;Herrera et al, 2002). Some alterations in blood biochemistry, including decrease in blood albumin and increase in globulin levels, hypoglycemia and increase in icterus index, have been reported in donkeys and horses (Soodan et al, 1996;Marques et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes

Cadioli¹,

Marques²,

Machado³

et al. 2006

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of the infected donkeys revealed a marked decline in hemoglobin, packed-cell volume, and erythrocyte count. Anemia was observed after successive peaks of parasitemia. Biochemical analyses showed increased levels of icterus index, serum globulins and decreased serum albumin and glucose values. All infected donkeys revealed enlargement of spleen and its white pulp, enlargement of mediastinal lymph nodes and lungs congestion. The main histopathological features consisted of meningoencephalitis. Demyelination in some areas of the cerebellum pediculus and neuropil vacuolization were observed. This study showed that donkeys infected with a Brazilian strain of T. evansi developed a chronic disease.

show abstract

“…The disease affects different body organs of infected animals which lead to alterations in serum biochemical parameters like liver enzymes, total proteins, glucose, cholesterol, albumin, urea, creatinine and minerals. Total proteins and gamma globulins increase while serum albumin decreases in several Trypanosomes infections (Herrera et al, 2002). Nevertheless, Katunguka-Rwakishaya et al (1999) and Osaeret al (2000) reported significant decline in total protein due to decreased albumin in sheep and ewes experimentally infected with T. congolense.…”

Section: Introductionmentioning

confidence: 99%

Review on Serum Biochemical Changes in Ruminants Infected with Major Trypanosome Species

2017

Int. J. Adv. Res. Biol. Sci

View full text Add to dashboard Cite

African trypanosomes are pathogens for humans and livestock. They are single-cell, extra-cellular parasites that cause persistent infections of the blood and induce profound immunosuppression. The life cycle of the African trypanosome begins when a tsetse fly feeds from an infected mammalian and the epidemiology depends on three factors, the distribution of the vectors, and the virulence of the parasite and the response of the host.The major pathogenic tsetse-transmitted trypanosome species are Trypanosoma congolense, T. vivax and T. brucei in cattle, sheep and goats and are found in the bloodstream and tissues of vertebrates throughout the world. However, these species are of overwhelming importance as a serious cause of morbidity and mortality in animals in tropical regions. There are no pathognomonic gross or histopathological lesions found in the animals that die of trypanosomiasis. Most of the observed lesions are due to the circulatory disturbances caused by anemia. Serum biochemical changes are characteristics of trypanosome infections, the severity of which are often determined by the strain of the infecting trypanosome and the host. It is known that pathophysiological alterations occur in the cellular and plasma components of blood during infection. The disease affects different body organs of infected animals which lead to alterations in serum biochemical parameters like liver enzymes, Total Proteins, Albumin, Glucose and Cholesterol. Hypoglycemia, which has been shown to occur during trypanosomosis, is reported to be due to excessive utilization of blood glucose by trypanosomes for their metabolism.Continuous utilization from the blood stream of cholesterol, phospholipids and total lipids also are a contributory factor to lowering of the serum levels of lipids and cholesterol. Thus, this manuscript reviews the serum biochemical changes and the major Trypanosoma species infecting ruminants.

show abstract

Experimental Trypanosoma evansi infection in South American coati (Nasua nasua): hematological, biochemical and histopathological changes

Cited by 43 publications

References 10 publications

Resposta eritropoética de ratos em diferentes graus de parasitemia por Trypanosoma evansi

Resposta eritropoética de ratos em diferentes graus de parasitemia por Trypanosoma evansi

Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes

Review on Serum Biochemical Changes in Ruminants Infected with Major Trypanosome Species

Contact Info

Product

Resources

About