Experimental testing of total knee replacements with UHMW-PE inserts: impact of severe wear test conditions

Zietz, Carmen; Reinders, Joern; Schwiesau, Jens; Paulus, Alexander; Kretzer, Jan Philippe; Grupp, Thomas M.; Utzschneider, Sandra; Bader, Rainer

doi:10.1007/s10856-015-5470-y

Cited by 20 publications

(20 citation statements)

References 89 publications

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“…However, it has been shown that variation in the experimental conditions, such as kinematic inputs and component alignment, will have an impact on the wear performance of a TKR. 10,[14][15][16] Indeed, different research centres have adopted different approaches to experimental wear simulation of TKRs, with different conditions all too common. The resulting contact point movement that these simulations produce will depend on the combination of many parameters including input displacement magnitudes, waveforms, direction of motion and femoral centre of rotation (CoR).…”

Section: Introductionmentioning

confidence: 99%

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The influence of simulator input conditions on the wear of total knee replacements: An experimental and computational study

Brockett

Abdelgaied

Haythornthwaite

et al. 2016

Proc Inst Mech Eng H

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Advancements in knee replacement design, material and sterilisation processes have provided improved clinical results. However, surface wear of the polyethylene leading to osteolysis is still considered the longer-term risk factor. Experimental wear simulation is an established method for evaluating the wear performance of total joint replacements. The aim of this study was to investigate the influence of simulation input conditions, specifically input kinematic magnitudes, waveforms and directions of motion and position of the femoral centre of rotation, on the wear performance of a fixed-bearing total knee replacement through a combined experimental and computational approach. Studies were completed using conventional and moderately cross-linked polyethylene to determine whether the influence of these simulation input conditions varied with material. The position of the femoral centre of rotation and the input kinematics were shown to have a significant influence on the wear rates. Similar trends were shown for both the conventional and moderately cross-linked polyethylene materials, although lower wear rates were found for the moderately cross-linked polyethylene due to the higher level of cross-linking. The most important factor influencing the wear was the position of the relative contact point at the femoral component and tibial insert interface. This was dependent on the combination of input displacement magnitudes, waveforms, direction of motion and femoral centre of rotation. This study provides further evidence that in order to study variables such as design and material in total knee replacement, it is important to carefully control knee simulation conditions. This can be more effectively achieved through the use of displacement control simulation.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The influence of simulator input conditions on the wear of total knee replacements: An experimental and computational study

Brockett

Abdelgaied

Haythornthwaite

et al. 2016

Proc Inst Mech Eng H

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“…Charnley preserved with polymer on metal combinations to maintain low frictional torques and introduced UHMWPE cups sliding on stainless steel femoral heads. This combination of materials has proved to be extremely successful giving low friction, low wear rates of the UHMWPE and smaller amounts of wear debris, which could be more readily tolerated by the body [10,11,20,21].…”

Section: Frictionmentioning

confidence: 99%

Failure Criteria of Artificial Joints: A review

Abdelbary

2019

ABEB

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This work is licensed under Creative Commons Attribution 4.0 License ABEB.MS.ID.000556.[15]. Research efforts are currently addressing the evaluation of the determinants affecting the overall wear rate of the artificial joint articulating surfaces, with the aim of reducing wear rate. However, one of the main challenges is the translation of research data from in vitro to in vivo environments [16]. For example, the wear debris produced by the hip joint simulator has a larger average size and wider distribution range compared to those from the implanted artificial joint [17]. The average diameter of the wear debris from joint simulator is 7.54 µm. The average diameter of the wear debris from artificial joint is 1.33 µm (about 18% of the wear debris from joint simulator).

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“…Some of the sources of experimental variability include the choice of displacement vs force control (Schwenke et al, 2009), differences in the lubricant (Brandt et al, 2010;Schwenke et al, 2005;Wang et al, 2004), the component starting position (Cheng et al, 2003;Zietz et al, 2015), and the effect of fluid absorption by the polyethylene, which can mask low wear rates (Schwenke et al, 2005). Another source of variability within TKR wear tests that has been identified is the definition of the femoral flexion/extension center of rotation (CoR) (Brockett et al, 2016;DesJardins and Rusly, 2011;Jennings et al, 2007;McEwen et al, 2005;Zietz et al, 2015). The location of femoral CoR location is also clinically relevant, as its position can vary surgically (Abdel et al, 2014;Rivière et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

The choice of the femoral center of rotation affects material loss in total knee replacement wear testing – A parametric finite element study of ISO 14243-3

Mell

Wimmer

2019

Journal of Biomechanics

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A leading cause of long-term failure of total knee replacements (TKRs) is osteolysis caused by polyethylene wear particles. The current gold standard for preclinical wear testing of TKRs is mechanical knee simulators. The definition of the femoral center of flexion-extension rotation (CoR) has been identified as one possible source of variability within TKR wear tests, since the femoral curvature varies from distal to posterior. The magnitude of the influence on wear due to changes in location of femoral CoR has not been investigated in depth. During this study, a computational framework utilizing finite element analysis for modelling wear of TKRs was developed and used to investigate the influence of the location of femoral CoR on TKR polyethylene wear during standardized displacement controlled testing (ISO 14243-3:2014). The study was carried out using a 40-point Latin Hypercube Design of Experiments approach. Volumetric wear was highly correlated to femoral CoR in both the superior/inferior and anterior/ posterior directions, with a stronger relationship in the superior/inferior direction. In addition, wear scars showing linear penetration were examined, with large differences in simulations at the extreme ends of the sampling region. In this study, it was found that variations in the location of the femoral center of rotation can represent a large source of variability in the preclinical testing and evaluation of the wear performance of total knee replacements. This study represents the first attempt at quantifying the effect on wear of different femoral center of rotations across a large sampling space.

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Experimental testing of total knee replacements with UHMW-PE inserts: impact of severe wear test conditions

Cited by 20 publications

References 89 publications

The influence of simulator input conditions on the wear of total knee replacements: An experimental and computational study

The influence of simulator input conditions on the wear of total knee replacements: An experimental and computational study

Failure Criteria of Artificial Joints: A review

The choice of the femoral center of rotation affects material loss in total knee replacement wear testing – A parametric finite element study of ISO 14243-3

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