Experimental study on thermic effects, morphology and function of guinea pig cochlea: A comparison between the erbium:yttrium–aluminum–garnet laser and carbon dioxide laser

Chi, Fang‐Lu

doi:10.1002/lsm.20647

Cited by 13 publications

(8 citation statements)

References 21 publications

(35 reference statements)

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“…The specific role that thermal damage plays in preservation of residual cochlear function is unknown. Similar to stapes surgery, minimizing thermal injury would be ideal during cochlear implantation 8. A major advantage of the CO 2 laser is the characteristic shallow depth of penetration in water of ∼10 μm 6.…”

Section: Discussionmentioning

confidence: 99%

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Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

et al. 2012

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Section: Discussionmentioning

confidence: 99%

“…Similar to stapes surgery, minimizing thermal injury would be ideal during cochlear implantation. 8 A major advantage of the CO 2 laser is the characteristic shallow depth of penetration in water of 10 lm. 6 The immediate absorption by fluid prevents deeper penetration to vulnerable cochlear structures.…”

Section: Discussionmentioning

confidence: 99%

Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

et al. 2012

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“…The detection procedure was well documented in our previous article [6]. A 0.8 mm diameter detecting head was placed onto the membrane of the round window to measure the temperature change at approximately one pulse per second during laser irradiation in vivo.…”

Section: Methodsmentioning

confidence: 99%

Analysis of the Damage Mechanism Related to CO₂Laser Cochleostomy on Guinea Pig Cochlea

Liu

Qian

et al. 2016

Neural Plasticity

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Different types of lasers have been used in inner ear surgery. Therefore, it is of the utmost importance to avoid damage to the inner ear (e.g., hyperthermia and acoustic effects) caused by the use of such lasers. The aim of this study was to use a high powered fibre-enabled CO2 laser (10 W, 606 J/cm2) to perform cochleostomies on guinea pig cochlea and to investigate the possible laser-induced damage mechanisms. The temperature changes in the round window membrane, auditory evoked brainstem response, and morphological of the hair cells were measured and recorded before and after laser application. All of the outcomes differed in comparison with the control group. A rise in temperature and subsequent increased hearing loss were observed in animals that underwent surgery with a 10 W CO2 laser. These findings correlated with increased injury to the cochlear ultrastructure and a higher positive expression of E-cadherin and β-catenin in the damaged organ of Corti. We assume that enhanced cell-cell adhesion and the activated β-catenin-related canonical Wnt-signalling pathway may play a role in the protection of the cochlea to prevent further damage.

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“…The laser source may either be continuous wave such as carbon dioxide lasers or pulsed lasers such as erbium:yttriumaluminium-garnet (Er:YAG), erbium:yttrium-scandiumgallium-garnet (Er:YSGG) and holmium:YAG. 25 Provided in their study involves the safety in relevance to total energy distribution and thermal generation with respect to laser irradiation towards the guinea pig cochlea.…”

Section: Consideration Of Laser Parameters Can Affect the Outcome Of ...mentioning

confidence: 99%

Effects of low-level laser therapy on utricular hair cell regeneration: a review of the efficacy of available treatment parameters

Cuenca

2022

Medical Lasers

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Low-level laser therapy (LLLT) for vestibular treatments need further development in the sense to be used in clinical applications. One hurdle of LLLT on vestibular treatment studies is the lack of relevant parameters other researchers can reference for further studies. In this paper, we would like to provide laser parameters that are currently used in different body parts which may prove effective on vestibular hair cell regeneration at the cellular level. Following relevant parameters for laser therapy, some irradiation techniques provide protective mechanisms against ototoxic damage. The following review includes the possible mechanisms of LLLT which promote cellular and tissue regeneration capabilities with promising results. These treatments may be of use in potentially mitigating functional decline under optimized irradiation conditions. This review focused on, but is not limited to, the availability of 633 nm and 808 nm LLLT administration. These treatments provide therapeutic results in different structures under in vitro, in vivo, or ex vivo conditions. The relevant findings on the use of LLLT show similar effects of irradiation regardless of the designated area of interest. This data suggests the possibilities of using similar or modified parameters of LLLT within the vestibular organs.

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Experimental study on thermic effects, morphology and function of guinea pig cochlea: A comparison between the erbium:yttrium–aluminum–garnet laser and carbon dioxide laser

Cited by 13 publications

References 21 publications

Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

Analysis of the Damage Mechanism Related to CO₂Laser Cochleostomy on Guinea Pig Cochlea

Effects of low-level laser therapy on utricular hair cell regeneration: a review of the efficacy of available treatment parameters

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Experimental study on thermic effects, morphology and function of guinea pig cochlea: A comparison between the erbium:yttrium–aluminum–garnet laser and carbon dioxide laser

Cited by 13 publications

References 21 publications

Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

Modification and comparison of minimally invasive cochleostomy techniques: A pilot study

Analysis of the Damage Mechanism Related to CO2Laser Cochleostomy on Guinea Pig Cochlea

Effects of low-level laser therapy on utricular hair cell regeneration: a review of the efficacy of available treatment parameters

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Analysis of the Damage Mechanism Related to CO₂Laser Cochleostomy on Guinea Pig Cochlea