Experimental Study on Interactions Between Selenium and Tin in Mice

Chiba, Momoko; Kamiya, Nobuko; Kikuchi, Masakazu

doi:10.1007/978-1-4612-4606-0_23

Cited by 1 publication

(2 citation statements)

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“…As a result, they reported that maximum selenium accumulation was happened in liver and spleen of mice 43 . In the study of Chiba et al (1987), it was suggested that selenium and Sn have maximum accumulation in bone, liver and spleen of mice. 29…”

Section: Discussionmentioning

confidence: 99%

“…24 female rats (220 gr average) were grouped in to 3 groups of 8 members and 100 µgr / Kg of nano-selenium, bulk sodium selenate and distilled water were injected intra-peritoneal (IP) in to first, second and third groups, respectively. Blood samples then collected at 24h and 48 h after injection [29][30][31] . These samples were centrifuged (5 min, 2000 rpm) and 500µl of serum was collected 30 .…”

Section: Absorption Of Nano-selenium and Bulk Selenium In Vivomentioning

confidence: 99%

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Biological Synthesis of Selenium Nanoparticles and Evaluation of their Bioavailability

Pouri

Motamedi

Honary³

et al. 2018

Braz. arch. biol. technol.

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Nanoparticles due to their unique properties have attracted more attention and their bacterial biosynthesis is more favorable because is environmental friendly and the size and yield of nanoparticles can be optimized. The aim of the present study was biosynthesis of Selenium nanoparticles using Bacillus cereus. For this purpose, bacterial culture was prepared in the presence of sodium selenate solution and incubated (30°C, 24 h). The produced nanoparticles were purified through consequent centrifugation, washing with 0.9% NaCl, sonication, washing with Tris-HCl containing Sodium dodecyl sulfate (SDS) and finally isolation with water-octanol two phase systems. Then using Ultraviolet-Visible spectroscopy, dynamic light scattering (DLS), scaning electron microscopy (SEM) and X-ray diffraction (XRD) analysis, nanoparticle production was confirmed. The bioavailability of nanoparticles was also investigated in rat. As a result of this study spherical selenium nanoparticles with a mean diameter of 170 nm were biosynthesized. MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration) of selenium for Bacillus cereus were same and equal to 75mM. Absorption and secretion of nanoselenium was significantly higher than bulk Selenium (P<0.05). In conclusion in the present study without any chemical substance, spherical Selenium nanoparticles were produced that do not have any environmental contamination. Furthermore, the metabolism of these particles suggests higher absorption rate of them that facilitates its application in medicine and also veterinary medicine.

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Section: Discussionmentioning

confidence: 99%