Experimental Study of Surface and Lattice Effects on the Solubility of Hydroxyapatite

Chuong, Robert

doi:10.1177/00220345730520054501

Cited by 41 publications

(22 citation statements)

References 4 publications

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“…This composition varies along with the chemical composition of the solution and all the possible chemical reactions at the surface. On the contrary, according to some authors, the effect of the surface on the HAp solubility has been disregarded [89].…”

Section: The Issue Of the Solubility And Its Consequences On The Nuclmentioning

confidence: 99%

About the Genetic Mechanisms of Apatites: A Survey on the Methodological Approaches

2017

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Apatites are properly considered as a strategic material owing to the broad range of their practical uses, primarily biomedical but chemical, pharmaceutical, environmental and geological as well. The apatite group of minerals has been the subject of a huge number of papers, mainly devoted to the mass crystallization of nanosized hydroxyapatite (or carboapatite) as a scaffold for osteoinduction purposes. Many wet and dry methods of synthesis have been proposed. The products have been characterized using various techniques, from the transmission electron microscopy to many spectroscopic methods like IR and Raman. The experimental approach usually found in literature allows getting tailor made micro-and nano-crystals ready to be used in a wide variety of fields. Despite the wide interest in synthesis and characterization, little attention has been paid to the relationships between bulk structure and corresponding surfaces and to the role plaid by surfaces on the mechanisms involved during the early stages of growth of apatites. In order to improve the understanding of their structure and chemical variability, close attention will be focused on the structural complexity of hydroxyapatite (HAp), on the richness of its surfaces and their role in the interaction with the precursor phases, and in growth kinetics and morphology.

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Section: The Issue Of the Solubility And Its Consequences On The Nuclmentioning

confidence: 99%

About the Genetic Mechanisms of Apatites: A Survey on the Methodological Approaches

2017

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“…Nearly all of these measurements were carried out in the ternary system, Ca(OH)2-H3P04 -H20, with the objective of using the simplest possible system to assure ease of interpretation of the data [1][2][3][4][5][6].1 In * This investigation was supported in part by Researc h Grant DEOO572 to th e Ame ri can Dental Association from the National Institute of Dp!ltal Re searc h and is part of th e de ntal research program conducted by the National Bur ~au of Standards in coo peration with th e American.Dental Association Health Foundatiw .. only one instan ce was a study made in a quaternary system (Ca5(P04hOH in the system Ca(OHh -H3P04 -H20 -HCl) [7]. In the present study, solubility measurements were extended to in clude the physiologically important salt, NaCl, as the fourth component.…”

Section: Introductionmentioning

confidence: 94%

“…Previous solubility studies on calcium phosphates [1][2][3][4][5][6][7] have shown that both of these equations for calculating ion activity coefficients are adequate; the ionic strengths of most of these solutions were less than 0.1.…”

Section: Introductionmentioning

confidence: 99%

Solubility of CaHPO4 2H2O in the quaternary system Ca(OH)2-H3PO4-NaCl-H2O at 25 C

Patel¹,

Grégory²,

Brown³

1974

J. RES. NATL. BUR. STAN. SECT. A.

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“…We have recalc ulated the solubility product using the adj ustm ent procedure desc ribed in this report; the resulting va lue of Ks is 5.23 (0.41) X 10-59 . Chuong [10] reported a series of IB measure ments on the four compone nt system Ca(OHh-H3 P04-H20 -H CI at 25 °C to ascertain the effect of varying the so lid-to-solution ratio; his solid was a portion of the same preparati on that was used in the present study. His results, shown in figure 3, cover only a narrow range of the pote ntial diagra m, but are seen to be consistent with the data of Avnime lec h et al There was a slight trend in KHA with increasing HCI conce ntrati on (mean values were 6.2 , 5.4 and 5.0 X 10-59 at HCI concentrations of 0.70, 1.0 and 10.0 mmol/L, respective ly), but no trend was observed at fixed acid concentrati on with solid-to-solution ratios varying from 0.2 to 2 .0 g/ 100 mL.…”

Section: Comparison With Reported Datamentioning

confidence: 99%

“…The data were used to calculate solubility products a nd thermod ynamic functions for this salt ta king into account ion pair formation. In addition to the work re ported here, we have re-examined solubility data obta ined a t 25°C in other studies [8][9][10] of hydroxyapatites pre pared in a manne r similar to the one used he re. The adjustm ent procedure [5,[11][12][13][14][15] used in treating the d ata is unusually ri gorous and provides a superior assessme nt of the re i iability of the de rived constants .…”

Section: Introductionmentioning

confidence: 98%

Solubility of Ca5{P04)3OH in the System Ca{OH)2-H3P04-H20 at 5, 15, 25, and 37 °C

McDowell¹,

Grégory²,

Brown³

1977

J. RES. NATL. BUR. STAN. SECT. A.

398

166

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Solubility isothe nns of hydroxyapatite, Ca5(PO.h OH (OHAp) , pre pa red by titrating a boiling aqueous suspe nsion of Ca(O HJ, with 0 .5 M H3PO., we re detennined in the te rnary system Ca(OHJ,-H3PO.-H20 at 5, 15, 25, a nd 3 7°C in the pH ra nge 3 .7-6. 7 by equilibration with dilute H3PO. solutio ns. The solubility product K" dete rmi ned as a fun ct io n of te mpe rature by a gene ra lized least-squa res procedure from 4 1 ex pe rimenta l points, is g ive n by the equationThe values of K s and it s dis persion at 25 a nd 37°C a re 3.04 (0.25) a nd 2.35 (0.27) X 10-59 . The re is a max imum in K s near 16°C, whic h may be d ue to the fo rm of te mperature de pendence found earlier fo r the sta bilit y constants of the ion pa irs Ca H2POt a nd Ca HPO~.The re lati ve pos itio ns of the isothe rms s how that OHA p has a negati ve the rma l coeffi cient of solub ility. T hermod ynam ic fun ctions for the di sso lutio n of the sa lt a re report ed .T he so lubility data previous ly re pOl1ed by others fo r OHAp at 25°C were rev iewed . The solubility prod uc ts obta ined by three of these in vestigators were compara ble with our value of 3 .0 X 10-59 ; thei r data were reeva luated by the method desc ri bed he re. We conclude that the best value fo r the so lubility p rod uct at 25 °c is 4.7 (2 .0) X 10-59 . Key wo rd s: Dissolution; hydroxyapatite; ion pa irs; sol ubility; so lu b ilit y isothe rms; so lu bility prod uct; the rmal coeffi c ient of solubilit y; thermod ynamics; tooth mine ra l.

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Experimental Study of Surface and Lattice Effects on the Solubility of Hydroxyapatite

Cited by 41 publications

References 4 publications

About the Genetic Mechanisms of Apatites: A Survey on the Methodological Approaches

About the Genetic Mechanisms of Apatites: A Survey on the Methodological Approaches

Solubility of CaHPO4 2H2O in the quaternary system Ca(OH)2-H3PO4-NaCl-H2O at 25 C

Solubility of Ca5{P04)3OH in the System Ca{OH)2-H3P04-H20 at 5, 15, 25, and 37 °C

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