The movement and deposition of particles that occur during their natural circulation in supercritical water exercise an important impact on the safe and stable operation of a supercritical water reactor (SCWR). When supercritical water flows in pipelines, a large number of corrosive particles may be generated due to pipeline corrosion or the purity of the fluid itself. The presence of particulate matter affects the heat transfer efficiency of the pipeline, increasing flow resistance and easily promoting heat transfer deterioration. ANSYS-CFX numerical analysis software was used to simulate the natural circulation loop of supercritical water, and micron particles were added in the initial flow field. The effects of heating power, particle concentration and particle diameter on particle deposition were obtained. Through this analysis, it can be concluded that the heating of the pipeline has a certain inhibitory effect on the deposition of particles. The rise in both initial particle concentration and particle diameter serve to reinforce the deposition of particles in the heating section. Depending on the degree of influence, the contributory parameters to particle deposition include particle diameter, particle concentration and heating power in turn.