Experimental studies on Trypanosoma (Schizotrypanum) cruzi strains isolated from man, from animals and from triatomine bugs in Brazil

Abstract

A study on nine strains of T. cruzi isolated from man, from animais and from triatomine bugs in Brazil are described.

Should Trypanosoma cruzi be called "cruzi" complex? A review of the parasite diversity and the potential of selecting population after in Vitro culturing and mice infection

“…Nowadays it is known that T. cruzi is an heterogeneous species consisting of several sub-populations of the parasite circulating among various wild and domestic vertebrates and invertebrate hosts (Morel et al 1986). Intra-specific variations among T. cruzi have been observed based on (i) the biological behavior of the strains in laboratory animals, (ii) biochemical features of the isolates, and (iii) molecular characteristics of the stocks (Bice & Zeledón 1970, Petana & Coura 1974, Miles et al 1977, Melo & Brener 1978, Morel et al 1980, Andrade 1985, Araújo & Chiari 1988, Carneiro et al 1991. In order to study the role of the parasite diversity in the pathogenesis of Chagas disease, a comprehensive characterization of the populations found in nature is crucial.…”