Experimental studies and nuclear model calculations on the formation of radioactive products in interactions of medium energy protons with copper, zinc and brass: Estimation of collimator activation in proton therapy facilities

Fassbender, Michael E.; Shubin, Yu.N.; Lunev, V.P.; Qaim, S.M.

doi:10.1016/s0969-8043(97)00102-4

Cited by 29 publications

(20 citation statements)

References 16 publications

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“…23,24]. In the present work, the excitation functions of the three nuclear reactions under consideration were calculated from their respective thresholds up to 67 MeV.…”

Section: Nuclear Model Calculationmentioning

confidence: 99%

Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu

Stoll¹,

Kastleiner²,

Shubin³

et al. 2002

Radiochimica Acta

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Proton induced reaction / Enriched target / Excitation function / Copper-67 / Gallium-66 and -67 / Chemical separationSummary. The excitation function of the 68 Zn( p, 2 p) 67 Cu reaction was measured radiochemically up to a proton energy of 71 MeV to obtain accurate data for production of the therapy related β − -emitting radioisotope 67 Cu (T 1/2 = 61.9 h). Investigations were also made on the ( p, 2n) and (p, 3n) reactions on 68 Zn. The experimental cross sections of the 68 Zn( p, 2 p) 67 Cu, 68 Zn( p, 2n) 67 Ga and 68 Zn( p, 3n) 66 Ga reactions were compared with published data and with theoretical predictions based on the hybrid-precompound model ALICE-IPPE. Thick target yields of 67 Cu, 67 Ga (T 1/2 = 78.3 h) and 66 Ga (T 1/2 = 9.4 h) were calculated. Production of 67 Cu is feasible only at proton energies above 50 MeV. For the target thickness E p = 70 → 50 MeV, the yield of 67 Cu amounts to 16.9 MBq/µA·h.

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“…23,24]. In the present work, the excitation functions of the three nuclear reactions under consideration were calculated from their respective thresholds up to 67 MeV.…”

Section: Nuclear Model Calculationmentioning

confidence: 99%

Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu

Stoll¹,

Kastleiner²,

Shubin³

et al. 2002

Radiochimica Acta

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“…Model calculations were performed using the code ALICE-IPPE, as described earlier [1], (for more detailed information cf.…”

Section: Nuclear Model Calculationsmentioning

confidence: 99%

“…We recently investigated the formation of activation products in beam collimator materials of proton radiation therapy facilities [1] and the generation of 7 Be in interactions of intermediate energy protons with light and medium mass elements of biological relevance [2], Now we report on (p,x) cross section data for the formation of 22 24 Na and other medium mass activation products like 44 "> 47 . 48 Sc, 48 V, 48 M Cr, 52 Fe and 55 Co etc.…”

Section: Introductionmentioning

confidence: 99%

Formation of Activation Products in Interactions of Medium Energy Protons with Na, Si, P, S, CI, Ca and Fe

1999

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“…Similarly the medium mass activation products are also not significant [26]. The activation of collimators, however, is appreciable [27] and due precautions are necessary to protect the therapy personnel. The formation of short-lived β + -emitters is of considerable scientific interest.…”

Section: Activation Productsmentioning

confidence: 99%

Nuclear data for medical applications: an overview

Qaim¹

2001

Radiochimica Acta

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A brief introduction to nuclear data in medicine is given. The choice of a radioisotope for medical application demands an accurate knowledge of radioactive decay data. Short-lived single photon and β + -emitters are preferred for diagnostic investigations, and longer-lived corpuscular radiation emitting radioisotopes for endoradiotherapy. The nuclear reaction cross section data, on the other hand, are needed for optimising the production routes. Besides radioactive isotopes, the use of ionising radiation in therapy is discussed. External radiation therapy has achieved an important place in medicine. The role of nuclear data is briefly discussed; they are needed for radiation dose calculations. The hitherto rather neglected activation products in proton therapy are considered. The methodology of development of a nuclear data file for medical applications is outlined.

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Experimental studies and nuclear model calculations on the formation of radioactive products in interactions of medium energy protons with copper, zinc and brass: Estimation of collimator activation in proton therapy facilities

Cited by 29 publications

References 16 publications

Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu

Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu

Formation of Activation Products in Interactions of Medium Energy Protons with Na, Si, P, S, CI, Ca and Fe

Nuclear data for medical applications: an overview

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Experimental studies and nuclear model calculations on the formation of radioactive products in interactions of medium energy protons with copper, zinc and brass: Estimation of collimator activation in proton therapy facilities

Cited by 29 publications

References 16 publications

Excitation functions of proton induced reactions on68Zn from threshold up to 71 MeV, with specific reference to the production of67Cu

Excitation functions of proton induced reactions on68Zn from threshold up to 71 MeV, with specific reference to the production of67Cu

Formation of Activation Products in Interactions of Medium Energy Protons with Na, Si, P, S, CI, Ca and Fe

Nuclear data for medical applications: an overview

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Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu

Excitation functions of proton induced reactions on⁶⁸Zn from threshold up to 71 MeV, with specific reference to the production of⁶⁷Cu