Experimental stapedectomy with collagen sponge implant

Biomedical applications of biodegradable polymers

“…Collagen sponges have been used as tissue supports and scaffolds for nearly 50 years. 465 Because of collagen's ability to withstand high tensile loads (92.5 MPa ultimate tensile strength), 466 it has often been used in bone tissue engineering. [467][468][469] Composites of hydroxyapatite and collagen are utilized, because these materials closely mimic the composition of natural bone.…”

Recent Advances in Otosclerosis

“…Sodium fluoride in daily doses of up to 60 mg has been used by several investi¬ gators, and it has apparently given marked relief of symptoms in these conditions. 6. The similarity of the pathologic picture of osteosclerosis produced by high intake of fluoride and that of mature otosclerotic le¬ sions prompted Shambaugh to try this drug therapeutically for the disease of otosclerosis.…”

Erratum: Buzdar AU, Guastalla J‐P, Nabholtz J‐M, et al. Impact of chemotherapy regimens prior to endocrine therapy: results from the ATAC (Anastrozole and Tamoxifen, Alone or in Combination) trial. Cancer. 2006; 107(3):472–80.

“…Because of collagen's structural integrity conveyed by its fibrous nature, a majority of biomedical research using collagen as a biomaterial has focused on its potential as a tissue engineering scaffold, specifically in load bearing applications. Collagen sponges have been used as tissue supports and scaffolds for nearly 50 years 465. Because of collagen's ability to withstand high tensile loads (92.5 MPa ultimate tensile strength),466 it has often been used in bone tissue engineering 467–469.…”