Designing a turbofan to operate in distorted inlet conditions is an issue of growing interest. In such conditions however, fan design can be computationally challenging. Indeed, subject to neither axi-symmetrical nor periodic inlet conditions, computations must be carried out throughout the whole circumferential domain i.e. 360°. Besides, the classical CFD approach implies the use of URANS computations so as to capture the distortion transfer across the fan stage. Eventually, computations are too onerous to be used in design loops. In this context, this paper presents a methodology to effectively assess a fan blade design domain in distorted conditions. This methodology is based on a body-force source term approach formulated in order to accurately recreate deviations, loads and losses across the fan stage. It notably enables to gain two orders in terms of restitution time and thus the possibility to use optimization tools. The design domain of this study is based on variations of profile chord, blade leading and trailing edges angles applied at two different relative heights. A Latin Hypercube Sampling (LHS) associated with a meta-model based on Radial Basis Functions (RBF) enables to assess the impact of geometric variations on performance and operability. Although this study emphasizes that some modeling improvements are still necessary, it also demonstrates the potential of the body-force methodology to conduct fan design when subject to inlet distortion.