Experimental myocardial infarction

Kumar, Raj; Joison, Julio; Gilmour, David P.; Molokhia, Farouk A.; Pegg, C. A. S.; Hood, William B.

doi:10.1172/jci106477

Cited by 9 publications

(1 citation statement)

References 26 publications

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“…To track Nodal activity, Dubrelle et al measured the nuclear accumulation of Smad2, the hallmark of Nodal signaling activation. To accurately quantify the nucleo-cytoplasmic ratio of Smad2, they generated a transgenic zebrafish line expressing GFP-Smad2 ubiquitously, and then observed the graded nuclear accumulation of GFP-Smad2 along the diffused Nodal gradient from vegetal to animal axis during blastula stage [ 16 ].…”

Section: Main Textmentioning

confidence: 99%

Transgenic fluorescent zebrafish lines that have revolutionized biomedical research

et al. 2021

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Since its debut in the biomedical research fields in 1981, zebrafish have been used as a vertebrate model organism in more than 40,000 biomedical research studies. Especially useful are zebrafish lines expressing fluorescent proteins in a molecule, intracellular organelle, cell or tissue specific manner because they allow the visualization and tracking of molecules, intracellular organelles, cells or tissues of interest in real time and in vivo. In this review, we summarize representative transgenic fluorescent zebrafish lines that have revolutionized biomedical research on signal transduction, the craniofacial skeletal system, the hematopoietic system, the nervous system, the urogenital system, the digestive system and intracellular organelles.

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Section: Main Textmentioning

confidence: 99%