Experimental investigations of the reservoir blood of the cat spleen: with special reference to haemolysis and the sedimentation reaction

Biometrically Revealed Splenic Differences between Thalassemia, Hereditary Spherocytosis and Elliptocytosis

“…This accumulation of sodium implies equally an accumulation of intracellular water, with consequent enlargement of the cell and subsequent osmotic-colloidal hemolysis (35). It is held this process takes place not only in blood-stream but mainly in the period spent by red cells in the spleen (20,48).…”