Edge preparation can improve tool life, cutting process stability, and quality of the machined surface. The coated tool must be edge-prepared after grinding to ensure enough bonding area to improve tool life. The influence of edge preparation on milling of aluminum alloy 211Z using the coated carbide tool is investigated via DEFORM simulations and corresponding cutting experiments. In this paper, the influence of edge radius, type of coating (TiN, TiCN, TiAlN, TiSiN, TiCrN), cutting speed, feed, axial depth, and radial depth on cutting force, surface roughness, and temperature is revealed. The results provide a basis for determining the effects of edge preparation. Moreover, theoretical values are used to reveal basic laws governing the cutting process, which may have practical significance.