“…19,21,22 Electromyographic evidence in monkeys with INO supports the presence of cocontracture of the medial rectus muscles with conjugate gaze. 4,19,21 Others describe an altered inhibitory input to the lateral rectus muscle or an adaptive alteration in the pulse and step signals from the parapontine reticular formation; the defect can be described as a pulse-step mismatch. 2,13,20,22 This latter hypothesis supports the authors' impression that strengthening the medial rectus muscles by resecting the muscles in WEBINO cases alters feedback to the neural integrators and somehow rectifies the pulse-step mismatch that causes the adduction lag and abducting nystagmus.…”