This paper presents the experimental observations and results of three one-quarter scale composite slab-beam systems, 3.15m by 3.15m in plan, and tested in fire conditions. The tests aimed to examine the effects of unprotected interior secondary beams and edge rotational restraint on the behaviour of floor assemblies. The test results show that continuity of reinforcement in the slab over the supporting beams, and the presence of interior beams, can reduce the slab deflection and enhance its load-bearing capacity. Interior beams can be left unprotected without leading to a structural failure. The interior beams play a major role in helping the slab to move from biaxial bending stage to membrane behaviour, enabling the slab to mobilize higher tensile membrane forces. Rotational restraint along the protected edge beams induces intense stress concentration above these beams, resulting in more severe concrete crushing at the four corners and wide cracks over the edge beams. The test results are compared to the Bailey-BRE method adopted in SCI publication P288. The method gives conservative results for the case with unprotected interior beams. However, it is recommended that it should not be applied for slab panels without interior beams because the failure mode for these was in a "brittle" mode which would occur suddenly. In addition to the experimental study, a numerical model using ABAQUS has been developed to simulate the tests. The numerical predictions agree well with the experimental results, showing that the proposed model is reliable.