Experimental evaluation of the culture parameters for optimum yield of lipids and other nutraceutically valuable compounds in Chloroidium saccharophillum (Kruger) comb. Nov

Santhakumaran, Prasanthkumar; Kookal, Santhosh Kumar; Mathew, Lizzy; Ray, Joseph George

doi:10.1016/j.renene.2019.09.071

Cited by 12 publications

(3 citation statements)

References 99 publications

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“…Similar to bacteria and fungi (Lo Grasso et al 2016), it is suggested that by changing conditions to induce cell stress, microalgae may be stimulated to produce secondary metabolites with antibacterial activity, as well as potentially larger quantities of these secondary metabolites (Ruffell et al 2016). Culture condition modifications include media composition, pH, light, and temperature (Schuelter et al 2019, Santhakumaran et al 2020b.…”

Section: Modified Culture Conditionsmentioning

confidence: 99%

Antibacterial compounds in green microalgae from extreme environments: a review

Little¹,

Senhorinho²,

Saleh³

et al. 2021

ALGAE

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Increased proliferation of bacterial resistance to antibiotics is a critical issue that has increased the demand for novel antibacterial compounds. Antibacterial activities have been evaluated in extracts from photosynthetic green microalgae, with varying levels of subsequent potential for development based on the strain of algae, strain of bacterial pathogen, and solvent used to extract the metabolites. Green microalgae from extreme environmental conditions have had to adapt to conditions that exclude many other organisms. The production of antibacterial compounds aids directly or indirectly in the survival of green microalgae in these extreme environments, as well as potentially serve other roles. This review investigates antibacterial activities of green microalgae from both extreme in-situ environmental conditions and induced extreme laboratory conditions and highlights.

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Section: Modified Culture Conditionsmentioning

confidence: 99%

Antibacterial compounds in green microalgae from extreme environments: a review

Little¹,

Senhorinho²,

Saleh³

et al. 2021

ALGAE

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show abstract

“…Previous studies suggested that modifying the culture conditions of green microalgae exhibited differences in antibacterial activity [47][48][49], whereas modifications on microalgae culture conditions could be stimulated to produce secondary metabolites with antibacterial activity, as well as potentially larger quantities of these secondary metabolites [50]. This may include modifications on media composition, pH, light, and temperature [51,52]. As an example, the highest light intensity (4800 lux) exposure effectively induced the production of antibacterial compounds by Dunaliella sp.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Antibacterial Activity of Marine Microalgae Extract against Vibrio harveyi

et al. 2022

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Marine microalgae may produce antibacterial substances. At the exponential phase of growth, four species of marine microalgae were examined for their potential to create secondary metabolites that limit the growth of Vibrio harveyi: Nannochloropsis oceanica, Chaetoceros gracilis, Isochrysis sp., and Thalassiosira weissflogii. V. harveyi is a pathogenic bacteria that can cause severe mortality and loss in aquaculture. Disc diffusion assay and co-culture assay were used to determine antibacterial activity. On TSA % NaCl media, the disc impregnated with microalgae and extracted with ethanol, methanol, saline water, and dimethyl sulfoxide (DMSO) was tested against V. harveyi at concentrations of 1.0 × 105, 106 and 107 CFU mL−1. The disc diffusion assay revealed that N. oceanica extracted with ethanol had the largest inhibitory zone against V. harveyi. Meanwhile, only N. oceanica, Isochrysis sp., and T. weissflogii reduced the growth of V. harveyi (105 CFU mL−1) in the co-culture assay (p < 0.05). The current findings reveal that the hydrophilic chemicals in microalgae extract have antibiotic activity against the highly virulent V. harveyi, which causes vibriosis, a serious disease in farmed fish and aquaculture cultivation around the world.

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“…Microalgae are recognized as a rich source of bioactive compounds such as proteins, polysaccharides, fatty acids (FAs), vitamins, antioxidants, and pigments (Edelmann et al, 2019;Farid et al, 2019;Safafar et al, 2015;Santhakumaran et al, 2020aSanthakumaran et al, , 2020bTang et al, 2020;Tossavainen et al, 2017Tossavainen et al, , 2019a, which can be utilized in several applications such as food and nutraceuticals, animal feed, cosmetics, plant growth stimulants and biofuels (Ariede et al, 2017;Chisti, 2008;Edelmann et al, 2019;Farid et al, 2019). Despite a recognized need for the use of natural bioactive ingredients in several industrial areas, microalgae are under-exploited, mainly as a consequence of high production and processing costs (Jacob-Lopes et al, 2019;Molina Grima et al, 2003).…”

Section: Introductionmentioning

confidence: 99%