Experimental Evaluation of Physical Breast Phantoms for 2D and 3D Breast X-Ray Imaging Techniques

Dukov, Nikolay; Bliznakova, Kristina; Teneva, Tsvetelina; Marinov, Stoyko; Bakić, Predrag R.; Bosmans, Hilde; Bliznakov, Zhivko

doi:10.1007/978-3-030-64610-3_62

Cited by 10 publications

(6 citation statements)

References 11 publications

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“…The experimental procedure requires: (a) physical models of the computational phantoms, shown in figure 2, and (b) experimental acquisition of x-ray images of these physical model at synchrotron facility with the same acquisition setup, shown in figure 1. For the creation of physical models, the 3D printing facilities in our laboratory will be used [30,31]. They will be placed on a hardware platform at a synchrotron beamline, providing x-rays, suitable for mammography applications.…”

Section: Resultsmentioning

confidence: 99%

Computational simulations and assessment of two approaches for x-ray phase contrast imaging

Bliznakova

Dukov

2022

J. Phys.: Conf. Ser.

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X-ray phase-contrast imaging is a high-resolution imaging that permits an increase of the perceptibility of the details in three-dimensional objects, such as human tissues compared to conventional absorption imaging. There are different approaches for implementing phase-contrast imaging and their introduction into clinical practice requires advanced computational tools. A long-term goal of our research is the development of computational models of breast phase-contrast imaging. The aim of this study is to develop a software module for implementing grating-based phase-contrast imaging. For this purpose, an existing in-house software application for x-ray imaging with a function to model and simulate propagation-based phase-contrast x-ray images has been extended to include a model of grating-based imaging. To test the new functionality, four computational phantoms reflecting features, which can be screened in the real breast tissue and which differ in their complexity, were designed. Planar x-ray images in absorption, propagation-based and grating-based modes were generated and compared. Results showed improved visual appearance of the simulated objects in images obtained by simulating grating-based imaging setup. The developed subroutine is planned to be experimentally validated at synchrotron facility. The new software functionality will be exploited in studies related to new x-ray imaging techniques for breast screening and diagnosing.

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Section: Resultsmentioning

confidence: 99%

Computational simulations and assessment of two approaches for x-ray phase contrast imaging

Bliznakova

Dukov

2022

J. Phys.: Conf. Ser.

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“…The accessibility of 3D printers offers flexibility in the production of specific phantoms to be used in biomedical sciences [13,14]. The manufactured phantoms can be used for different purposes, including the optimisation of medical imaging device settings and imaging techniques [15,16].…”

Section: Introductionmentioning

confidence: 99%

Utilisation of 3D Printing in the Manufacturing of an Anthropomorphic Paediatric Head Phantom for the Optimisation of Scanning Parameters in CT

et al. 2023

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Computed tomography (CT) is a diagnostic imaging process that uses ionising radiation to obtain information about the interior anatomic structure of the human body. Considering that the medical use of ionising radiation implies exposing patients to radiation that may lead to unwanted stochastic effects and that those effects are less probable at lower doses, optimising imaging protocols is of great importance. In this paper, we used an assembled 3D-printed infant head phantom and matched its image quality parameters with those obtained for a commercially available adult head phantom using the imaging protocol dedicated for adult patients. In accordance with the results, an optimised scanning protocol was designed which resulted in dose reductions for paediatric patients while keeping image quality at an adequate level.

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“…One means of controlling the density (as required for CT phantoms) is to vary the filament extrusion rate (per unit time) on a pixel-by-pixel basis while maintaining a constant printing speed. A similar approach was used by Okkalidis et al [12]- [17]. in conjunction with edge detection and morphological operations to enhance and separate organs.…”

Section: Introductionmentioning

confidence: 99%

Design and fabrication of 3D-printed patient-specific soft tissue and bone phantoms for CT imaging

Mei

Pasyar

Geagan

et al. 2023

Preprint

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The objective of this study is to create patient-specific phantoms for computed tomography (CT) that have realistic image texture and densities, which are critical in evaluating CT performance in clinical settings. The study builds upon a previously presented 3D printing method (PixelPrint) by incorporating soft tissue and bone structures. We converted patient DICOM images directly into 3D printer instructions using PixelPrint and utilized stone-based filament to increase Hounsfield unit (HU) range. Density was modeled by controlling printing speed according to volumetric filament ratio to emulate attenuation profiles. We designed micro-CT phantoms to demonstrate the reproducibility and to determine mapping between filament ratios and HU values on clinical CT systems. Patient phantoms based on clinical cervical spine and knee examinations were manufactured and scanned with a clinical spectral CT scanner. The CT images of the patient-based phantom closely resembled original CT images in texture and contrast. Measured differences between patient and phantom were less than 15 HU for soft tissue and bone marrow. The stone-based filament accurately represented bony tissue structures across different X-ray energies, as measured by spectral CT. In conclusion, this study demonstrated the possibility of extending 3D-printed patient-based phantoms to soft tissue and bone structures while maintaining accurate organ geometry, image texture, and attenuation profiles.

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Experimental Evaluation of Physical Breast Phantoms for 2D and 3D Breast X-Ray Imaging Techniques

Cited by 10 publications

References 11 publications

Computational simulations and assessment of two approaches for x-ray phase contrast imaging

Computational simulations and assessment of two approaches for x-ray phase contrast imaging

Utilisation of 3D Printing in the Manufacturing of an Anthropomorphic Paediatric Head Phantom for the Optimisation of Scanning Parameters in CT

Design and fabrication of 3D-printed patient-specific soft tissue and bone phantoms for CT imaging

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