Experimental design for novel in-vitro dissolution method validation for lamivudine-150mg and zidovudine-300mg film-coated tablets

Abstract

The present study objective is Experimental Design for novel in- vitro Dissolution method validation for Lamivudine150 and Zidovudine 300 mg film-coated tablets and its provide the direction to design and conduct performance test for the same and established documentary evidence through the test method defined in the study , its helps to demonstrate that the chromatographic analytical methods for determination of dissolution in Lamivudine/Zidovudine 150 mg/300 mg film-coated tablets Films coating tablet will yield consistent, reliable and reproducible results within in the pre-determined acceptance criteria The active ingredient Lamivudine and Zidovudine and Inactive ingredients include microcrystalline cellulose, sodium starch glycolate, colloidal silicon dioxide, povidone, magnesium stearate, and opadry white (composed of Hydroxy Propyl methylcellulose 2910/Hypromellose 5cP, Titanium dioxide, and Polyethylene glycol 400).