Experimental Design and Data Collection

Quantitative description of Listeria monocytogenes inactivation kinetics with temperature and water activity as the influencing factors; model prediction and methodological validation on dynamic data

“…This type of design permits the investigation of some combinations of the environmental factors of interest (see, for example, Neter, Kutner, Nachtsheim, & Wasserman, 1996;Rasch, 2004). The experiments were performed in inoculated macerated potato and were initiated once the desired temperature and water activity were reached.…”

Inactivation of Escherichia coli O157:H7, Salmonella Typhimurium and Listeria monocytogenes by underwater shock waves

“…When studying the effects of a given treatment, one can choose between using a single strain or a mixture of different strains (Rash, 2004). We decided to work with a single strain of each pathogen because inactivation of a cocktail of strains could yield data that would be difficult to interpret.…”

Modeling the growth, survival and death of microbial pathogens in foods

“…A number of formal statistical designs may be used to help design microbiological modeling experiments (Davies, 1993;McMeekin et al, 1993;Ratkowsky, 1993;Rasch, 2004;van Boekel and Zwietering, 2007). Even so, for the microbiologist beginning a modeling study there is no substitute for involving a good statistician or mathematician at all stages of experimental design, experimentation and data analysis.…”

“…Unfortunately for experimenters the 'marginal' conditions are usually the hardest to work in! Several authors have given detailed descriptions of experimental design for modeling in food microbiology (Davies, 1993;McMeekin et al, 1993;Ratkowsky, 1993;Rasch, 2004;van Boekel and Zwietering, 2007). Guidelines for data collection and storage are given by Kilsby and Walker (1990) and Walker and Jones (1993).…”