Experimental Creation of Fusiform Carotid Artery Aneurysms Using Vein Grafts in Rats

Abstract

Recurrent hemorrhaging from intrathrombotic vascular channels caused dissection between the thrombus and the aneurysm wall, which led to growth of the experimental aneurysms to giant aneurysms. With this model, we demonstrated the growth mechanism of giant fusiform aneurysms.

Application of the Willis covered stent using the telescopic technique for the treatment of fusiform aneurysm in a canine model

“…[14,15] Fukui et al [16] initially constructed fusiform aneurysms in rats by surgical venous grafting and the pathological findings were similar to those observed in human intracranial aneurysms. This technique has since been applied in large animals, including dogs and swine among others.…”

Imaging of intracranial aneurysms in animals: a systematic review of modalities

“…In 1993, Hashimoto [ 31 ] used this modality to measure blood flow velocity in a rabbit venous pouch IA model. Since then, this technique has been used in a number of IA studies to study blood flow velocity in cerebral arteries or within the IA and to check IA patency over time or after treatments [ 41 , 42 , 44 , 91 , 154 , 176 , 178 ].…”

“…[ 38 ] 1996 X Surgical Rats Saccular X X Spetzger U. [ 39 ] 1996 X Surgical Rabbits Saccular X Bavinzski G. [ 40 ] 1998 X Surgical Rabbits Saccular X Fukui K. [ 41 ] 1998 X Surgical Rats Fusiform X X Kallmes D.F. [ 42 ] 1999 X Surgical Dogs Saccular X X ...…”