Experimental correction of footdrop by electrical stimulation of the peroneal nerve

Waters, R L; McNeal, Donald R.; Perry, Jacquelin

doi:10.2106/00004623-197557080-00002

Cited by 136 publications

(80 citation statements)

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“…Implantable neural prostheses for foot drop generally use nerve-cuff electrodes to activate the motor nerves and lift the foot, and some record sensory information to trigger stimulation [1][2]4,[6][7][8][9][10][11][12][13]. However, most implantable neural prostheses provide only dorsiflexion to correct foot drop and do not provide active plantar flexion.…”

Section: Neural Prostheses For Ankle Controlmentioning

confidence: 99%

“…It has two major terminal branches, the tibial nerve and common fibular nerve. The common fibular (common peroneal) branches into the deep and superficial fibular (SF) nerves and is commonly targeted in neural prostheses used to correct foot drop [1][2][3][4][5]. The deep fibular (DF) branch innervates the tibialis anterior muscle, which dorsiflexes and inverts the foot.…”

Section: Introductionmentioning

confidence: 99%

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Human distal sciatic nerve fascicular anatomy: Implications for ankle control using nerve-cuff electrodes

Gustafson

Grinberg

Joseph

et al. 2012

JRRD

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Abstract-The design of neural prostheses to restore standing balance, prevent foot drop, or provide active propulsion during ambulation requires detailed knowledge of the distal sciatic nerve anatomy. Three complete sciatic nerves and branches were dissected from the piriformis to each muscle entry point to characterize the branching patterns and diameters. Fascicle maps were created from serial sections of each distal terminus below the knee through the anastomosis of the tibial and common fibular nerves above the knee. Similar branching patterns and fascicle maps were observed across specimens. Fascicles innervating primary plantar flexors, dorsiflexors, invertors, and evertors were distinctly separate and functionally organized in the proximal tibial, common fibular, and distal sciatic nerves; however, fascicles from individual muscles were not apparent at these levels. The fascicular organization is conducive to selective stimulation for isolated and/or balanced dorsiflexion, plantar flexion, eversion, and inversion through a single multicontact nerve-cuff electrode. These neuroanatomical data are being used to design nerve-cuff electrodes for selective control of ankle movement and improve current lower-limb neural prostheses.

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Section: Neural Prostheses For Ankle Controlmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Human distal sciatic nerve fascicular anatomy: Implications for ankle control using nerve-cuff electrodes

Gustafson

Grinberg

Joseph

et al. 2012

JRRD

View full text Add to dashboard Cite

show abstract

“…Another feature is that the dynamic equations of motion, i.e., MQ = ? : + f + 6, (2) do not have to be linearized. In (2), which was derived using Kane's method ever, with dynamic programming is that each of the continuous variables describing the state of the system (i.e., the q's and q ' s ) must be represented, for the purposes of comparing the controls, by discrete approximations.…”

Section: Obtaining the Suboptimal Controlsmentioning

confidence: 99%

“…footdrop during hemiplegic gait [ 11, [2] and to enable paraplegic gait 131-[SI. Although virtually every application of FNS for paraplegic ambulation has relied heavily upon external, weight-supporting devices and/or extensive bracing systems, FNS-assisted gaits have been sustained for several hours each day, covering distances up to one kilometer [9].…”

Section: Introductionmentioning

confidence: 99%

Restoring unassisted natural gait to paraplegics via functional neuromuscular stimulation: a computer simulation study

Yamaguchi

Zajac

1990

IEEE Trans. Biomed. Eng.

249

111

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Abstract-Functional neuromuscular stimulation (FNS) of paralyzed muscles has enabled spinal-cord-injured patients to regain a semblance of lower-extremity control, for example to ambulate while relying heavily on the use of walkers. Given the limitations of FNS, specifically low muscle strengths, high rates of fatigue, and a limited ability to modulate muscle excitations, it remains unclear, however, whether FNS can be developed as a practical means to control the lower extremity musculature to restore aesthetic, unsupported gait to paraplegics.A computer simulation of FNS-assisted bipedal gait shows that it is difficult, but possible to attain undisturbed, level gait a t normal speeds provided the electrically-stimulated ankle plantarflexors exhibit either near-normal strengths or are augmented by an orthosis, and at least seven muscle-groups in each leg are stimulated. A combination of dynamic programming and a n open-loop, trial-and-error adjustment process was used to find a suboptimal set of discretely-varying muscle stimulation patterns needed for a 3-D, 8 degree-of-freedom dynamic model to sustain a step. An ankle-foot orthosis was found to be especially useful, as it helped to stabilize the stance leg and simplified the task of controlling the foot during swing. It is believed that the process of simulating natural gait with this model will serve to highlight difficulties to be expected during laboratory and clinical trials.

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“…Muscles acting on the fingers and thumb have been stimulated with intramuscular electrodes to provide active palmar or lateral prehension in quadriplegics [16,17], and gait deficits in stroke and spinal-cord-injured patients have been partially cor rected by stimulation of muscles controlling movement at the hip, knee and ankle [13,14,18,23,26].…”

Section: Introductionmentioning

confidence: 99%

Response of Single Alpha Motoneurons to High-Frequency Pulse Trains

Bowman

McNeal²

1986

Stereotact Funct Neurosurg

157

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Studies were conducted on 25 cats to document the discharge rates of alpha motoneurons during stimulation of the sciatic nerve at frequencies from 100 to 10,000 pulses per second (pps). In addition, the feasibility of using high-frequency pulse trains to block the conduction of action potentials was investigated. Two cuff electrodes were placed around the proximal portion of the left sciatic nerve, and recordings of antidromic potentials were taken from single fibers of the L7 ventral root. When stimulating through the more proximal electrode, discharge rates were generally equal to or were subharmonics of the stimulation rate up to 1,000 pps. Firing often decreased in rate during 3-min runs. At 2,000–10,000 pps, fibers responded briefly at rates of several hundred per second but stopped firing within seconds after stimulus initiation. After cessation of response to the high-frequency pulse train, action potentials generated at 50 pps at the more distal electrode did not propagate to the recording electrodes. The ‘electrical block’ so induced was maintained for up to 20 min, and recovery following termination of the pulse train was complete within 1 s.

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Experimental correction of footdrop by electrical stimulation of the peroneal nerve

Cited by 136 publications

References 0 publications

Human distal sciatic nerve fascicular anatomy: Implications for ankle control using nerve-cuff electrodes

Human distal sciatic nerve fascicular anatomy: Implications for ankle control using nerve-cuff electrodes

Restoring unassisted natural gait to paraplegics via functional neuromuscular stimulation: a computer simulation study

Response of Single Alpha Motoneurons to High-Frequency Pulse Trains

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