Experimental choices for the determination of carbonyl compounds in air

Abstract

The analysis of carbonyls in ambient air has received a great deal of scientific attention with the advancement of analytical techniques and increased demand for the build-up of its data base. In this review article, we have attempted to provide some insight into the relative performance of different instrumental approaches available for the analysis of ambient carbonyls with a major emphasis on high performance liquid chromatographic and gas chromatographic methods. Reported in several international standard procedures, derivatization of carbonyls with 2,4-dinitrophenylhydrazine (2,4-DNPH) with either an impinger or cartridges is the most commonly used method of HPLC detection. In this respect, a number of alternative hydrazine reagents have also been discussed for use with HPLC. In contrast, GC methods based on the combined application of adsorptive enrichment on solid sorbents and thermal desorption are examined with regard to their suitability for carbonyl analysis in air. Particular emphasis has been directed towards the advantages and drawbacks of these different instrumental techniques for ambient carbonyls. Based on this comparative approach, we discuss the suitability for each method for carbonyl analysis.

Development of a paper-based approach for the detection of carbonyl compounds in indoor air samples

“…After six hours, paper-based devices were analyzed using FTIR and image scanner method. A second set of devices exposed to the standard formaldehyde air samples for a period of six hours were extracted in to a solution of methanol and the methanol extract was analyzed using HPLC (Pal et al, 2007).…”

“…An enclosed air tight room space contaminated with formaldehyde was tested using the paper-based devices and HPLC (Pal,et al, 2007) and FTIR methods were used to quantify the levels of CC in the air tight room. Two methods were compared statistically at 95% confidence limit using the method explained in Skoog et al…”

“…However 2,4-di-nitrophenyl hydrazine (2,4-DNPH) is the most commonly used derivatization agent (Szulejko et al, 2015). Even though there are few drawbacks (Pal et al, 2007), the 2,4-DNPH derivatization-based HPLC method can be considered as a cheaper and easier methods for the determination of CC. However, the use of advanced instruments such as HPLC-UV/VIS and GC/MS methods are not suitable to monitor the onsite CC levels under nonlaboratory conditions.…”

Influences of sampling volume and sample concentration on the analysis of atmospheric carbonyls by 2,4-dinitrophenylhydrazine cartridge

“…niques [11]. HPLC-based analysis of carbonyls has received widespread acceptance due to the presence of stable hydrazones that form carbonyl derivatives such as 2,4-dinitrophenylhydrazine (2,4-DNPH) [2,[12][13][14].…”

Turn on Fluorescent Probes for Selective Targeting of Aldehydes

“…As a result, aldehydes are frequently released to the environment, and their presence needs to be monitored [1,2]. Methods to monitor aldehydes include simple colorometric measurements [3][4][5][6][7], and more involved electrochemical, gas chromatography, and chemiluminiscent techniques [8][9][10][11][12][13][14]. One common approach is to detect the product of the reaction of an aldehyde with an aromatic hydrazine.…”