Experimental caprine coccidiosis: the pattern of changes in antioxidant micronutrients and vitamins

Abstract

This study aimed at investigating the status of non-enzymatic antioxidant agents during experimental caprine coccidiosis. A total of 20 newborn kids were selected and allocated into 2 (diseased and healthy) groups. Ten of the kids were infected with sporulated oocysts of the most pathogenic species of <em>Eimeria</em> and ten served as controls. Blood samples were taken at 0 (before inoculation), 3, 7, 14, 21, 28 and 35 days post infection (dpi) and the concentrations of antioxidant trace elements, antioxidant vitamins and ceruloplasmin were measured. Our data showed remarkable reductions in serum concentrations of some antioxidant trace elements (zinc, manganese and selenium) and vitamins (vitamin C) in the diseased kids, however, significant increases were observed in the serum level of ceruloplasmin in infected animals. These alterations became more prominent at 14 to 21 dpi. These observations suggest that <em>Eimeria</em> parasites can significantly interfere with the levels of some antioxidant trace elements and vitamins during caprine coccidiosis. These changes indicate the overproduction of oxidative radicals during the pathogenesis of <em>Eimeria</em> species that may account for extensive oxidative damage in infected animals.

Effect of Tick and Lice on Some Blood Constitute and Trace elements of Local Black Goat in Sulaimani, Kurdistan Region of Iraq

“…In the Measureable reduction of zinc and copper in the infested goat statistically (p≤0.01) in compares with control goats, the present study is parallel to which it reached by [1] in high zinc decreased (p≤0.01) in infested sheep with compare to non infested sheep in Sulaimani and also agree with the same cached result by [10] in the diseased animal. Also the present study is absolutely concur to [23] was observed highly decreased in Zn and Cu, statistically (p≤0.01) in infected sheep, also agree with [24] as they detected significance differences (p≤0.05) in some trace elements particularly in Zn, in infested goats, while our results are vary to [25] as they observed, increase of Cu with significance differences (p≤0.05) and decreases of Zn without any significances (p≥0.05) in diseased sera in comparing with healthy sera. As in the Table 3 was illustrated, in all results, influence of lice is less than both mixed infestation and tick infested goat, this result have agreement with [17] but with varying in serum protein as in their study effect of lice are more on this parameter than ticks, except of copper whole other parameters (serum proteins and zinc) has not any differences (p≥0.05) among them.…”

Parasitism-Induced Changes in Microbial Eukaryotes of Peruvian Alpaca Gastrointestinal Tract

“…Giardia sp. does not directly impact hemoglobin levels [51], in the same way that Eimeria lamae does not affect hemoglobin levels [52]. However, both pathogens induce diarrheal conditions, diarrhea can lead to a series of perturbations in the immune system.…”

Evaluation of The Efficacy of Oxytetracycline on Experimentally Induced Caprine Coccidiosis Due to Eimeria arloingi Infection.

“…The material filtered was centrifuged for 10 minutes at 250 g. The supernatant was then removed. Oocysts sporulation was achieved by using 2.5% (w/v) potassium dichromate solution as described by Rakhshandehroo et al (2014). Identification of the oocysts specie was done as reported by Rakhshandehroo et al (2014).…”