Experimental Assessment of the Impact of Adverse Factors of Titanium-Magnesium Production

Abstract

Іn order to clarify the nature of pathological changes in animals that develop under the influence of a complex of toxic gases and dust (titanium dioxide aerosol, titanium metal dust, titanium tetrachloride and its hydrolysis products, as well as chlorine and phosgene), we performed experimental studies directly in the conditions of titanium-magnesium production. This approach, from our point of view, can create the most profitable experimental model that allows for the maximum completeness of the corresponding clinical and experimental Parallels. Therefore, a series of experimental animals were placed on the territory of the three main workshops of JSC «CC TMK». The animals were placed in specially made cages of 25-26 heads each, which were installed at the level of the human respiratory system. Experimental animals of the control series of the experiment were kept on the territory of the plant, but at a considerable distance from the main production shops in a separate, clean, well-ventilated room. The animals of the control group were slaughtered at the same time as the experimental animals. These studies help in the development of evidence-based measures to improve the health of workers engaged in harmful working conditions. In such production conditions, workers often had acute respiratory infections, chronic bronchitis, etc.the degree of retention of compounds containing chlorine anion (chlorine, hydrogen chloride, titanium tetrachloride, phosgene, magnesium dihloride) was relatively high and ranged from 39-85%. At the same time, higher indicators of the degree of delay in all the main workshops were usually observed for gaseous substances (chlorine, hydrogen chloride, phosgene), which is probably due to their good solubility.