Experimental And Theoretical Studies of Green Synthesized Cu2O Nanoparticles Using Datura Metel L

Chinnaiah, K.; Maik, Vivek; Kannan, Karthik; Потемкин, В. А.; Grishina, Maria; Gohulkumar, M.; Tiwari, Ratnesh; Gurushankar, K.

doi:10.21203/rs.3.rs-804953/v1

Cited by 3 publications

(1 citation statement)

References 26 publications

(14 reference statements)

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“…The energy of incident light is provided by a catalyst with bandgap energy equal to or greater than that of photocatalysts. The bandgap energy was calculated by the Tauc formulation, (αhν) 1/n= A (hν− Eg), in which his Planck's constant, ν is vibration frequency, α is absorption coefficient, Eg is bandgap energy, and A is a proportionality constant and n is sample transition behavior [13].…”

Section: 2mentioning

confidence: 99%

Enhanced photocatalytic and Antibacterial Activity of Copper oxide Nanoparticles Synthesized by Facile Combustion methods from Mussaendafrondosa Plant Extract

Babitha¹,

Christy²,

Palani

et al. 2022

Phys. Chem. Solid St.

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Microwave heating (MHM) and mutated sol-gel (SGM) mechanisms were used to effectively create CuO samples with two dissimilar morphologies, such as nanoparticles (CuO-NPs) and nanorods (CuO-NRs), using Mussaendafrondosalinn plant extract as the bio-reducing operator. X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX) investigations were used to analyze the sample's structure, pureness, and morphological characteristics. UV-Visible diffuse reflectance (DRS) and photoluminescence (PL) spectroscopy methodologies were used to analyze optical properties and calculate bandgap energy. The bandgap of the samples was measured using the Kubelka-Munk mechanism, and it was found to be 2.74eV and 2.33eV for CuO-NPs and CuO-NRs, correspondingly. CuO-NPs and CuO-NRs were investigated for antibacterial activity versus each Gram-positive and Gram-negative microorganisms using a modified disc diffusion method. When correlated to the sample CuO nanorods, the antibacterial study confirms that the sample CuO nanoparticles are high-grade antibacterial agents. Using solar lighting, the photocatalytic activity of CuO nano-reactants (CuO-NPs and CuO-NRs) for the degradation of methylene blue (MB) dye was investigated, and the findings revealed that CuO-NPs with tinier particle sizes degraded MB more than CuONRs.

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Section: 2mentioning

confidence: 99%

Enhanced photocatalytic and Antibacterial Activity of Copper oxide Nanoparticles Synthesized by Facile Combustion methods from Mussaendafrondosa Plant Extract

Babitha¹,

Christy²,

Palani

et al. 2022

Phys. Chem. Solid St.

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Effect of copper nanoparticles green-synthesized using Ocimum basilicum against Pseudomonas aeruginosa in mice lung infection model

Wang,

Liu,

Han

2024

Open Chemistry

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The frequency of lung infection induced by multi-drug resistant strains of Pseudomonas aeruginosa has significantly risen, primarily due to the inadequate effectiveness of powerful chemotherapeutic methods. This study demonstrates that the Ocimum basilicum aqueous extract and copper nanoparticles (CuNPs) exhibited significant antioxidant and anti-infectious properties under in vivo conditions. To analyze the characteristics of the CuNPs synthesized from the reaction between copper nitrate solution and the aqueous O. basilicum extract, various techniques such as energy dispersive X-ray analysis, field emission scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction analysis, and transmission electron microscopy were employed. The in vivo study encompasses the assessment of P. aeruginosa lethal dose in mice and the disease manifestation analysis, which comprises reduction in body weight, hypothermia, bacteremia, and other parameters, over a 48 h infection period. The infected mice exhibited a notable decrease in body temperature, measuring at 25°C after 48 h, compared to the initial temperature of 39°C. Additionally, a 30% reduction in weight was seen at the conclusion of the study. To assess the effectiveness of CuNPs on lung infection caused by the calculated lethal dose and bacteremia, histopathology analysis was employed. The bacterial load in the CuNPs group was determined to be 0.5 Log10CFU/mL on Day 8, indicating a notable decrease from the initial measurement of 1.5 Log10CFU/mL on Day 1. The histopathological findings revealed a widespread and sporadic buildup of alveolar space inflammatory cells, with infiltrates observed throughout all lung sections in infected mice. Enhanced lung histology was observed in the group of animal treated with reduced exudates noted at 200 µg/kg. CuNPs demonstrated inhibitory effects on the growth of P. aeruginosa at 8 µg/mL, while at 16 µg/mL, they effectively eradicated P. aeruginosa. The research unequivocally demonstrates the efficacy of CuNPs extract in combating lung infections induced by P. aeruginosa at 200 µg/kg. The recent survey aims to further explore the biomedical characteristics of these CuNPs in order to develop a powerful treatment against this dangerous pathogen.

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Preparation, characterization, and determination of the therapeutic effects of copper nanoparticles green-formulated by Pistacia atlantica in diabetes-induced cardiac dysfunction in rat

Lin,

Jiang,

Zhou

et al. 2024

Open Chemistry

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The development and creation of innovative therapeutic supplements and medications with extraordinary efficacy for addressing severe diabetes are of utmost importance to both developing and developed nations. A bio-inspired method has been documented for producing copper nanoparticles (CuNPs) using Pistacia atlantica leaf extract as a natural stabilizing agent. This approach is applicable, easy, and environmentally friendly, as it avoids using any toxic or harmful reagents. The CuNPs that were synthesized through biological processes underwent characterization using sophisticated physicochemical methods such as energy-dispersive X-ray spectroscopy, transmission electron microscopy, field emission-scanning electron microscopy, and Fourier-transformed infrared spectroscopy. It is confirmed that CuNPs exhibit a spherical structure, with an average size ranging from approximately 30 to 70 nm. Diabetes was induced in vivo through a fructose-enriched diet combined with streptozotocin. Half the subjects were administered CuNPs (100 µg/kg) via oral gavage. In contrast to the animals that were given regular food, the diabetic animals revealed an increase in serum fasting glucose level and a decrease in glucose tolerance. The administration of CuNPs had a significant impact on reducing glucose intolerance and fasting hyperglycemia. Additionally, it helped alleviate the negative effects of diabetes on cardiac output and work. Furthermore, utilizing CuNPs effectively hindered the rise in cardiac signal transducer and activator of transcription 3-phosphorylation caused by diabetes. The findings from this investigation provide evidence of the therapeutic benefits of CuNPs in mitigating diabetes-induced cardiac dysfunction in rats.

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Experimental And Theoretical Studies of Green Synthesized Cu2O Nanoparticles Using Datura Metel L

Cited by 3 publications

References 26 publications

Enhanced photocatalytic and Antibacterial Activity of Copper oxide Nanoparticles Synthesized by Facile Combustion methods from Mussaendafrondosa Plant Extract

Enhanced photocatalytic and Antibacterial Activity of Copper oxide Nanoparticles Synthesized by Facile Combustion methods from Mussaendafrondosa Plant Extract

Effect of copper nanoparticles green-synthesized using Ocimum basilicum against Pseudomonas aeruginosa in mice lung infection model

Preparation, characterization, and determination of the therapeutic effects of copper nanoparticles green-formulated by Pistacia atlantica in diabetes-induced cardiac dysfunction in rat

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