Among the renewable sources, woody biomass combustion is still the most diffused for domestic heating and, in the last decades, domestic pellet stoves have spread widely due to their simplicity and to the high energy density of the pelletized fuel. In several regions of North Italy, the legislator limited the type of pellet fuels that can be used. Only A1-plus pellets, which is obtained from clean wood processing, is allowed. However, the abundance of residual biomasses, from vine and hemp seasonal pruning, rises the possibility of their thermal valorization in domestic pellet stoves. In this paper, hemp hurd and vine pruning derived pellets were tested as fuel into a commercial pellet stove of 9 kW nominal thermal power and a comparison was made in terms of combustion efficiency and pollutant emissions. On the one hand, the tests shown similar results between A1+ and vine pellets in terms of efficiency while the emissions of CO increased by 10-times. On the other hand, hemp derived pellets generate thermal efficiency 3-times lower than pellet A1+ and slightly higher emissions.