Experimental and clinical studies with radioactive colloidal gold in the therapy of serous effusions arising from cancer

Moses, Campbell; Kent, Edward M.; Boatman, Joseph B.; Cole, R D; Sunder, J. H.; George, Robert S.; Russ, Clem; Ford, William B.; Kutz, Eugene R.

doi:10.1002/1097-0142(1955)8:2<417::aid-cncr2820080222>3.0.co;2-w

Cited by 16 publications

(3 citation statements)

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“…Colloidal Au nanoparticles have been employed as adjuvants in clinical radiotherapies for many years (particularly for brachytherapy) [4][5][6]139], but functionalized GNRs must be regarded as novel combination products and thus require the same pharmacokinetic testing as any other novel chemical entity. The many examples presented here amply demonstrate the feasibility of employing GNRs as multifunctional agents for biomedical diagnostics and image-guided therapies.…”

Section: Discussionmentioning

confidence: 99%

Gold Nanorods as Theranostic Agents

Wei

Leonov

2011

Nanoplatform‐Based Molecular Imaging

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Section: Discussionmentioning

confidence: 99%

Gold Nanorods as Theranostic Agents

Wei

Leonov

2011

Nanoplatform‐Based Molecular Imaging

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“…(iv) The 'long-term' control of hypercalcxmia complicating malignant disease rests in the control of the disease by medical (Nathanson and Kelley, 1952) or surgical means.…”

Section: Biochemical Techniquesmentioning

confidence: 99%

General Medical Aspects of Malignant Disease

Matthias

1961

Postgraduate Medical Journal

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“…Nanoparticles have been used in biology and medicine for over 50 years (Kreuter, 2007). Experimental and clinical studies with radioactive colloidal gold in the therapy of serious effusions arising from cancer (Moses et al, 1955). In earlier times, they were generally called colloids, emulsions or aerosols, and included many natural and man-made suspensions.…”

Section: Introductionmentioning

confidence: 99%

Imaging and therapy with radionuclide labeled magnetic nanoparticles

Ünak

2008

Braz. arch. biol. technol.

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Magnetic nanoparticles offer exciting new opportunities including the improvement of the quality of magnetic resonance imaging (MRI), hyperthermic treatment for malignant cells, site-specific drug delivery and also the recent research interest of manipulating cell membranes. The biological applications of these nanomaterials require these nanoparticles to have high magnetization values, size smaller than 20 nm, narrow particle size distribution and a special surface coating for both avoiding toxicity and allowing the coupling of biomolecules. In this review, we focus on the feasibility of radionuclide labeled magnetic nanoparticles, as drug carriers, and summarize recent advances in this field.
Nanopartículas magnéticas oferecem novas oportunidades interessantes, incuindo a melhora da qualidade da imagem de ressonância magnética (MRI), no tratamento hipertérmico para células malignas, na administração de medicamentos sítio-específicos e também no recente interesse da manipulação de membranas celulares. As aplicações biológicas desses nanomateriais requer que essas nanopartículas tenham valores altos de magnetização, tamanho menor que 20 nm, partículas de dimensão de distribuição restrita e um revestimento especial de superfície para evitar a toxicidade e permitir o acoplamento de biomoléculas. Nessa revisão, focalizamos na viabilidade de nanopartículas magnéticas marcadas com radionuclídeos, como transportadoras de medicamentos, e resumimos os recentes avanços nesse campo

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Experimental and clinical studies with radioactive colloidal gold in the therapy of serous effusions arising from cancer

Cited by 16 publications

References 0 publications

Gold Nanorods as Theranostic Agents

Gold Nanorods as Theranostic Agents

General Medical Aspects of Malignant Disease

Imaging and therapy with radionuclide labeled magnetic nanoparticles

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