2019
DOI: 10.52571/ptq.v16.n32.2019.838_periodico32_pgs_820_832.pdf
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Experiencing a Synthesis One-Pot of 1,2,4-Oxadiazole Mediated by Microwave Oven: Green Chemistry in Focus

Abstract: 1,2,4-oxadiazoles are compounds that have attracted the attention of many researchers due to their wide range of biological activities, for example, anti-inflammatory, antimicrobial, antitumor etc. The syntheses are based mostly on the use of amidoximes and acylating agents as the initial reactants. This work aims to describe a one-pot reaction for the synthesis of 1,2,4-oxadiazols, mediated by microwave irradiation, employing home-use microwave oven, in the discipline of heterocyclic Chemistry in the postgrad… Show more

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