Experiences with the Treatment of Cystic Craniopharyngiomas by Stereotactically Injected Radioisotopes

Sturm, Volker; Georgi, P.; Netzeband, H.; Scheer, K. E.; Strauss, L.; Schlegel, Wolfgang; Scharfenberǵ, H.; Sinn, H.; Gahbauer, H; Penzholz, H.

doi:10.1007/978-3-642-95413-9_44

Cited by 3 publications

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“…Thus, almost all ra dioactivity is delivered within 2 weeks. However, the relatively high en ergy of 90Y may occasionally cause radiation-induced side-effects, as reported by Sturm et al [6] and shown in this study. In dealing with small thin-walled cysts, 32P may be the agent of choice, as it has a lesser degree of tissue penetration and a longer half-life than 90Y.…”

Section: Discussionsupporting

confidence: 50%

“…The method of stereotactic intra-cavitary irradiation was first described by Leksell and Linden in 1952 and further standardized by Backlund et al [4] in 1972. Recently, en couraging clinical results and a high incidence of cyst regression after such treatment have been reported by some authors [5][6][7][8][9][10], The present report describes a 6-year experience in 18 consecutive patients who un derwent stereotactic treatment for cystic craniopharyngiomas.…”

Section: Introductionmentioning

confidence: 95%

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Stereotactic Internal Irradiation for Cystic Craniopharyngiomas: A 6-Year Experience

Pan

Lee

Huang

et al. 1990

Stereotact Funct Neurosurg

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Fourteen adults and 4 children with cystic craniopharyngiomas were treated with stereotactic β-irradiation during a 6-year period. Of these patients, 10 were primary cases, and 8 were recurrences after previous major surgery. Radioactive phosphorus (³²P) or yttrium (⁹⁰Y) in colloidal forms were used as the radiation agents. Cyst volumes (10–130 ml) were assessed intraoperatively by the ⁹⁹Tc radiodilution method. According to our treatment program, the radiation dose to the cyst wall was 20,000 rad and the total irradiation time 2 weeks. The follow-up period ranged from 1 to 6 years, with an average of 3.8 years. Postoperative shrinkage of the cysts and clinical improvement were observed in most patients. Pertinent clinical data and results of treatment are described.

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Section: Discussionsupporting

confidence: 50%