“…The potential role of frozen RBC in the prevention of post-transfusion hepati tis was first suggested by Tullis et al [16], but, although he found no case of hepatitis after transfusion of frozen red cells, the number of cases in the control group was consid ered too small for the data to be conclusive. Other retro spective clinical reports suggested a beneficial effect [11,12,27,28]. In contrast, Alter et al [29] showed that hu man red cells dosed with HBV could still transmit hepati tis B to chimpanzees after freezing.…”