“…(Cooper) Insofar as the ability to demonstrate a nuanced, open and non-judgmental understanding of the sexual lives of patients is an important factor in HIV healthcare (cf. Palich et al, 2017), there is something of a resonance here with what Maria Puig de la Bellacasa (2017:4) has argued for as 'a politics of care' that, as she puts it, 'engages much more than a moral stance; it involves affective, ethical, and hands-on agencies of practical and material consequence'. Nevertheless, given our interviewees were at the front line of approaching health as a static condition, presumed to be preserved against a pathological viral or bacterial agent (Canguilhem, 1989) or, indeed, a potentially destructive 'chemsex' drug (McCall et al, 2015), much of what we have included here suggests that PrEP not only warrants a reconfiguring of the prevailing conceptions of risk but, more particularly, how it aligns with what can be made possible for the cultures it is intended to serve.…”