Experiences and outcomes of organ-sparing surgery for testicular tumour with benign tendency

Abstract

Introduction: We retrospectively investigated and summarized our experiences and the outcomes of organ-sparing surgery (OSS) for testicular tumour with benign tendency. Methods: From April 2000 to March 2012, 11 selected patients with testicular tumour underwent OSS. Preoperative and postoperative organ functional and oncologic indexes were analyzed and compared. Results: All operations were completed without conversion to radical orchiectomy. Intraoperative frozen section and routine postoperative pathology showed tumours with benign tendency. The normal appearance of the scrotum and functional integrity of the testis were preserved. Preoperative and postoperative serum sex hormone levels, international index of erectile function (IIEF-5) scores, and semen quality were not significantly different. Tumour recurrence or metastasis did not occur during follow-up. Conclusions: Our results showed the feasibility and safety of OSS to treat testicular tumour with benign tendency. With careful selection and rigorous follow-up, some testis tumor can be treated with OSS to maximally maintain normal appearance and function of the testis. The retrospective single-centre study and small sample size are main limitations. More evidence is needed to establish the large-scale application of OSS.

Testis-sparing surgery: Experience in 13 patients with oncological and functional outcomes

“…It has also been shown that organ sparing surgery is a reasonable and reliable alternative for testicular tumors with benign tendency. 16 Preservation of the testicular function holds importance in terms of preventing the postoperative erectile dysfunction (ED). ED is seen in 31.5% of patients after radical orchiectomy.…”

“…19 Liu et al reported no significant changes between preoperative and postoperative sperm concentrations and motilities in 11 patients with TSS history due to benign testicular tumors. 16 The risk of recurrence in the contralateral testis in patients with who had malign testicular tumors was reported to be between 1.8% and 2.8%. 20 The most common bilateral testicular tumor is seminoma that can present with metachronous metastasis in 4 years.…”

Redo Surgery in Childhood Testicular Tumors

“…İkincisi, bu kitlelerde canlı tümör varlığını öngören iyi bir görüntüleme keşfedilmiştir: 18-fluoro-deoxyglucose positrson emission tomografi (FDG-PET). FDG-PET ve tümör belirteçleri kullanılarak kemoterapi sonrası RPLND kararı Günümüzde intraoperatif frozen biyopsi olanağının yaygın kullanılmaya başlaması, dikkatli hasta seçimi ve yakın takip ile bazı testis tümörleri fonksiyonel testis dokusu bırakmak adına organ koruyucu cerrahi ile tedavisi bildirilmiştir (29,30). Çalışmamızda psikolojik ve kozmetik etkileri göz önünde bulundurularak preoperatif değerlendirme sonrasında benign karakter taşıyan beş olguya testis koruyucu cerrahi uygulanmıştır.…”

Germ Cell Neoplasia in situ (GCNIS) in Testis-Sparing Surgery (TSS) for Small Testicular Masses (STMs)

“…Moreover, it has been reported that unilateral orchiectomy has disruptive effects on overall spermatogenesis (4). Liu et al reported no significant changes in terms of sperm concentrations and motility in 11 patients with TSS history for benign testicular tumors (12).…”