Experience with remifentanil–sevoflurane balanced anesthesia for abdominal surgery in neonates and children less than 2 years

Michel, Fabrice; Lando, A.; Aubry, Christine; Arnaud, S; Merrot, Thierry; Martin, Claude

doi:10.1111/j.1460-9592.2008.02514.x

Cited by 17 publications

(10 citation statements)

References 21 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In neonates and infants, 1.0 MAC of sevoflurane induces a decrease of 30% in blood pressure but the heart rate is not modified, suggesting an important baroreflex inhibition [64,65]. In children older than 5 years, 1.0 MAC has no effect on blood pressure or heart rate, whereas halothane is responsible for hypotension [64].…”

Section: Cardiovascular Effectsmentioning

confidence: 97%

Sevoflurane inside and outside the operating room

Michel

Constantin

2009

Expert Opinion on Pharmacotherapy

Self Cite

View full text Add to dashboard Cite

Background: Sevoflurane is often presented as a near-perfect anaesthetic. After 10 years in the operating room, new uses are emerging outside. Objective: To remind readers of the principal characteristics of sevoflurane, to affirm its usefulness for day-case anaesthesia and to consider the recent new uses. Methods: The discussion of the physical properties, pharmacokinetics, metabolism, mechanisms of action and clinical effects is based on classic, essential papers. Recent literature concerning emerging utilizations of sevoflurane was analysed. Results: Sevoflurane presents many benefits with minimum inconvenience. It allows rapid inhalation induction, maintenance and rapid recovery. It has little toxicity and its haemodynamic and respiratory depressive effects are moderate and well tolerated. It is already widely use for sedation for magnetic resonance imaging in children. Its use in paediatric or adult intensive care could improve the management of pain and sedation.

show abstract

Section: Cardiovascular Effectsmentioning

confidence: 97%

Sevoflurane inside and outside the operating room

Michel

Constantin

2009

Expert Opinion on Pharmacotherapy

Self Cite

View full text Add to dashboard Cite

show abstract

“…This infant was the only patient outside the neonatal age range, which might suggest that these slightly older infants require higher dosages. However, many infants of this age are effectively treated with much lower remifentanil doses during surgery [25][26][27].…”

Section: Interval After Start Of Study-medication (Hours)mentioning

confidence: 99%

Remifentanil/midazolam versus fentanyl/midazolam for analgesia and sedation of mechanically ventilated neonates and young infants: a randomized controlled trial

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Michel et al. (29) carried out a retrospective, observational study involving 63 children distributed among three groups: premature newborns (n = 18), full‐term newborns (n = 21) and children under 2 years of age (n = 24) submitted to abdominal surgery with the use of continuous remifentanil infusion combined with sevoflurane inhalation anaesthesia. Episodes of hypotension occurred in 66.6% of the premature newborns, 58.3% of the full‐term newborns and 75% of the children under 2 years of age.…”

Section: Pharmacodynamicsmentioning

confidence: 99%