Experience With a Digital Computer for Study and Improved Management of the Critically Ill

Towards integrative physiological monitoring of the critically ill: from cardiovascular to microcirculatory and cellular function monitoring at the bedside

“…One can argue that this characteristic - namely, the continuous monitoring and support of physiological variables - defines the health of critically ill patients. The introduction by Weil and Safar of monitors attached to digital computers to continuously monitor respiratory and hemodynamic measurements was a defining moment in the development of critical care medicine [1]. This technology, used in conjunction with the pulmonary artery catheter introduced by Swan [2], provided the intensivist with a powerful platform to semicontinuously monitor the functional state of the heart as the main motor driving systemic circulation.…”

50 Years of Sepsis Investigation/Enlightenment Among Adults—The Long and Winding Road

“…"Efforts are increasingly directed to the construction of mathematical models of basic pathophysiology and techniques by which such models may be used to simulate and thereby predict the effects of selected treatments*. " *Weil et al (213) (first president of SCCM [Weil MH]) commenting in 1966 in Journal of the American Medical Association on initial experience with a digital computer for study of management of the critically ill in their shock research unit at University of Southern California School of Medicine.…”

EDV-Vermessung von Ekg-Kurven bei Telemetrieversuchen

“…Die manuelle Auswertung von Ekg-Kurven , ist besondel's bei Verlaufslmtersuchungen sehr zeitraubend, Bei geeigneten EDV-Anlagen konnen Biopotentiale in Form einer elektrischen Sparmlmg direkt aufgenommen und verarbeitet werden [2,5,7,8,13,14,23,24,26,28,29,30,31,32,64,69,83,84]. Die automatische Bearbeitlmg von menschlichen Elektrokardiogrammen hat groBe Verbreitlmg geflU1.den [1,'-3, 11, 12, 16, 19, 20, 21, 22, 25, 27, 33, 34, 35, 38, 43, 46, 49, 51, 54, 56, 57, 58, 59].…”