“…Change detection is a fundamental behavioral capacity of animals and humans (Rensink, 2002;Elmore et al, 2011;Hagmann and Cook, 2013;Pearson and Platt, 2013), and the visual cortex of mice and primates is implicated in the detection of changes in visual features (Womelsdorf et al, 2006;Glickfeld et al, 2013;Brunet et al, 2014). The core task we describe can be used to test perception of various visual features including orientation, contrast, color, and natural images (Glickfeld et al, 2013;Denman et al, 2018;Garrett et al, 2020). Moreover, our task includes features that permit investigation of the physiological correlates of behavior and cognition.…”