Experience of the first lung transplantation performed in public sector in India

Prasad, Kuruswamy Thurai; Sehgal, Inderpaul Singh; Dhooria, Sahajal; Agarwal, Ritesh; Singh, Ramandeep; Singh, Harkant; Puri, Goverdhan Dutt; Arya, Virendra K.; Behera, Digambar; Aggarwal, Ashutosh N.

doi:10.4103/lungindia.lungindia_74_18

Cited by 5 publications

(3 citation statements)

References 16 publications

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Section: History and Transplant Volumes Of Live And Deceased Donor Tr...mentioning

confidence: 99%

“…During the coronavirus disease 2019 (COVID-19) pandemic, transplantation rates initially declined in India 5 and gradually recovered with the implementation of National Organ and Tissue Transplant Organization transplant guidelines 6,7 and the ability to cope with the pandemic. Table 2 summarizes milestones in SOT in India [8][9][10][11][12][13][14][15][16][17][18][19] Heart-Lung Transplants At the time of this report, there were <10 government institutions performing heart transplant (Figure 2B…”

Section: History and Transplant Volumes Of Live And Deceased Donor Tr...mentioning

confidence: 99%

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Current Status, Challenges, and Opportunities of Organ Donation and Transplantation in India

et al. 2023

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DISCREPANCY BETWEEN LIVE AND DECEASED DONOR TRANSPLANTS IN INDIAWe intend to elaborate on the current status, diversity in access, equity, and economics of solid organ transplantation (SOT) in India. Currently, India performs the third largest volume of organ transplants after the United States and China. [1][2][3] Notably, <10% of patients with organ failure have access to SOT worldwide. The Indian Ministry of Health estimates a gap of approximately 175 000 kidneys, 50 000 livers, hearts, and lungs in addition to 2500 pancreas. TheNewsletter Transplant (2018 data) reported on 12 758 patients wait-listed for kidneys, 4173 for liver, 425 for heart, 75 for lung, 48 for pancreas, and 6 for small bowel transplants (SBTs) for in India. 4 Deceased donation rates have remained stable and <1 per million population from 2013 to 2021. To achieve self-sufficiency in organ donation, the estimated deceased donation rate in India will need to achieve a rate of 62 per million population. The distinguishing feature of Indian transplant programs is their predominant reliance on living donation (87%), with only 13% of the kidney transplant volume deriving from deceased donors (DD). [1][2][3] There are also stark geographic differences in India with active DD programs in South and West India, whereas DD has not been initiated in Northeast India. Moreover, donation after the circulatory determination of death and kidney-paired exchange programs are still underdeveloped in India (<1%) and should be promoted.

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Section: History and Transplant Volumes Of Live And Deceased Donor Tr...mentioning

confidence: 99%

Section: History and Transplant Volumes Of Live And Deceased Donor Tr...mentioning

confidence: 99%

Current Status, Challenges, and Opportunities of Organ Donation and Transplantation in India

et al. 2023

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“…Lung transplantation is the only therapeutic option that can be offered to silicosis patients with end-stage fibrosis; the outcomes are like those for other ILDs [104]. However, successful lung transplant programmes are sparse in most developing countries [105][106][107].…”

Section: Treatmentmentioning

confidence: 99%

Silica-associated lung disease in developing countries

Dhooria

Sehgal

Agarwal

2022

Current Opinion in Pulmonary Medicine

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Purpose of reviewThere is a considerable burden of silica-associated lung diseases in the developing world. This review summarizes the epidemiology of these diseases, especially silicosis and silico-tuberculosis, mitigative efforts and treatment, especially in the context of developing countries.Recent findingsIn 2017, the highest incidence of silicosis was in China, India and Brazil among the developing countries. The prevalence of silicosis amongst exposed workers may vary from 4 to 55%; there is a risk of underestimation because of the ‘healthy worker effect’. The permissible exposure limit for respirable silica adopted by governments in developing countries remains higher than the proposed 0.025 mg/m3. Silica exposure in informal or unorganized industries is challenging, as it falls outside statutory controls. Recent efforts on regulation and compensation by various governments in developing countries are encouraging but need proper implementation on the ground. Biomarkers such as club cell protein 16 and imaging methods such as computed tomography may offer earlier and easier detection of silicosis. Advanced silicosis remains incurable; novel treatments such as antifibrotics agents may be potentially effective.SummarySilica-associated lung diseases are prevalent in developing countries. Efforts directed at preventing or minimizing exposure to respirable crystalline silica are required for mitigation.

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The evolution of lung transplantation in India and the current scenario

Sunder

2021

Indian J Thorac Cardiovasc Surg

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Experience of the first lung transplantation performed in public sector in India

Cited by 5 publications

References 16 publications

Current Status, Challenges, and Opportunities of Organ Donation and Transplantation in India

Current Status, Challenges, and Opportunities of Organ Donation and Transplantation in India

Silica-associated lung disease in developing countries

The evolution of lung transplantation in India and the current scenario

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