Experience of intravenous sedation for pediatric gastrointestinal endoscopy in a large tertiary referral center in a developing country

Amornyotin, Somchai; Aanpreung, Prapun; Prakarnrattana, Ungkab; Chalayonnavin, Wiyada; Chatchawankitkul, S.; Srikureja, Wichit

doi:10.1111/j.1460-9592.2009.03063.x

Cited by 39 publications

(36 citation statements)

References 25 publications

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“…Additionally, more profound falls in blood pressure occur in a hypovolemic patient. Propofol has also been proven to reduce postprocedural hypoxemic events, which may be of significance in critically ill elderly patients [20,21] and sick pediatric patients [22,23] . Prevention of this complication is to take a relevant medical and drug history before the procedure with particular detail required regarding current antihypertensives, antianginal and antiarrhythmic therapy and the use of systemic corticosteroids.…”

Section: Complicationsmentioning

confidence: 99%

Sedation-related complications in gastrointestinal endoscopy

Amornyotin

2013

WJGE

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106

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Sedation practices for gastrointestinal endoscopic (GIE) procedures vary widely in different countries depending on health system regulations and local circumstances. The goal of procedural sedation is the safe and effective control of pain and anxiety, as well as to provide an appropriate degree of memory loss or decreased awareness. Sedation-related complications in gastrointestinal endoscopy, once occurred, can lead to significant morbidity and occasional mortality in patients. The risk factors of these complications include the type, dose and mode of administration of sedative agents, as well as the patient's age and underlying medical diseases. Complications attributed to moderate and deep sedation levels are more often associated with cardiovascular and respiratory systems. However, sedation-related complications during GIE procedures are commonly transient and of a mild degree. The risk for these complications while providing any level of sedation is greatest when caring for patients already medically compromised. Significant unwanted complications can generally be prevented by careful pre-procedure assessment and preparation, appropriate monitoring and support, as well as post-procedure management. Additionally, physicians must be prepared to manage these complications. This article will review sedation-related complications during moderate and deep sedation for GIE procedures and also address their appropriate management.© 2013 Baishideng Publishing Group Co., Limited. All rights reserved. Key words: Sedation; Complication; Gastrointestinal; EndoscopyCore tip: Gastrointestinal endoscopic (GIE) procedures are relatively safe. However, these procedures have been shown to cause various effects on cardiorespiratory systems. Sedation-related complications while providing any level of sedation can occur. Fortunately, these complications during GIE procedures are commonly transient and of a mild degree. In addition, significant unwanted complications can generally be prevented by careful pre-procedure assessment and preparation, appropriate monitoring and support. Periodical assessment of the level of sedation and continuous monitoring of cardiovascular and respiratory systems provides timely information. Standardized discharge criteria should be used to determine the patient's readiness for discharge.Amornyotin S. Sedation-related complications in gastrointestinal endoscopy.

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Section: Complicationsmentioning

confidence: 99%

Sedation-related complications in gastrointestinal endoscopy

Amornyotin

2013

WJGE

Self Cite

106

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“…Although hypotension and hypertension during endoscopy very rarely result in permanent complications, they occasionally reach levels for which corrective action is appropriate. Atrial or ventricular arrhythmias are rarely precipitated by sedation or stress of the procedure (4,5,7,12,17,18). In works of Deenadayalu et al (19) a worldwide multicenter safety review of more than 521,000 patients was conducted.…”

Section: Discussionmentioning

confidence: 99%

Retrospective analysis of deep sedation in pediatric population for endoscopic procedures: adverse events and outcomes

et al. 2015

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“…Propofol, which is preferred due to its short duration of action, has been reported to provide a deep sedation and rapid recovery, but when used alone, propofol cannot provide adequate immobility and a relatively higher dose of propofol is required to enable adequate sedation (2,5,6). At times, such high doses may result in hypotension, respiratory depression, and unintended duration of anesthesia (7).…”

Section: Introductionmentioning

confidence: 99%

“…Opioids have been reported to reduce the need for propofol, in addition to providing hemodynamic stability and increasing the performance of the endoscopist by providing ease of procedure (2,(6)(7)(8)(9)(10). Different combinations of these agents were studied in pediatric anesthesia literature (2,8,10,11).…”

Section: Introductionmentioning

confidence: 99%

The safety and efficacy of remifentanil compared to fentanyl in pediatric endoscopy

Gül¹,

Hızlı²,

Kocamer³

et al. 2013

Turk J Med Sci

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N-{[(4-bromophenyl)amino]carbonothioyl}benzamide was synthesized and characterized by IR, 1 H-and 13 C-NMR, mass spectrometry, and elemental analysis. The crystal structure was determined from single crystal X-ray diffraction data. It crystallizes in monoclinic space group P2 1 /n with unit cell dimensions a = 13.822(3)Å, b = 5.927(2)Å, c = 16.642(3)Å, and β = 103.963(3) • . There is a strong intramolecular hydrogen bond of the type N H Λ O, with an H Λ O distance of 2.6129 (11)Å. The mass fragmentation pattern is also discussed.

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Experience of intravenous sedation for pediatric gastrointestinal endoscopy in a large tertiary referral center in a developing country

Abstract: In the setting of the developing country, intravenous sedation for pediatric GIE by trained anesthetic personnel with appropriate monitoring was safe and effective. Serious adverse events were rare in our population.

Cited by 39 publications

References 25 publications

Sedation-related complications in gastrointestinal endoscopy

Sedation-related complications in gastrointestinal endoscopy

Retrospective analysis of deep sedation in pediatric population for endoscopic procedures: adverse events and outcomes

The safety and efficacy of remifentanil compared to fentanyl in pediatric endoscopy

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