Experience of a tertiary pandemic centre on the labour and delivery of 337 pregnant women with COVID-19: a prospective cohort study from Turkey

Uygur, Dilek; Erol, Seyit Ahmet; Anuk, Ali Taner; Tokalıoğlu, Eda Özden; Yetiskin, Fatma Didem Yucel; Besimoğlu, Berhan; Oğuz, Yüksel; Ayhan, Şule Göncü; Altınboğa, Orhan; Unlu, Serpil; Özcan, Namık; Keskin, Hüseyin Levent; Tekın, Özlem Moraloğlu

doi:10.1080/01443615.2022.2039907

Cited by 1 publication

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…COVID 19 is related to potential numerous adverse pregnancy related outcomes including significantly higher primary and prelabor caesarean delivery rates. Maternal chronic disease, obstetric complication, severe/critical COVID-19 infection, ICU admission, oxygen support, tocolysis, antenatal corticosteroid prophylaxis, induction failure, NICU admission, postpartum worsening in maternal condition and antibiotic use were higher in the covid positive primary cesarean section groups [ 21 ]. There are reports of worse manifestation in pregnant women infected by new SARS-COV2 variant.…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic changes associated with neuraxial anesthesia in pregnant women with covid 19 disease: a retrospective case-control study

et al. 2022

View full text Add to dashboard Cite

Background Neuraxial blocks is the recommended mode of analgesia and anesthesia in parturients with Coronavirus 19 (COVID-19). There is limited data on the hemodynamic responses to neuraxial blocks in COVID-19 patients. We aim to compare the hemodynamic responses to neuraxial blocks in COVID-19 positive and propensity-matched COVID-19 negative parturients. Methods We conducted retrospective, cross-sectional case–control study of hemodynamic changes associated with neuraxial blocks in COVID-19 positive parturients in a Tertiary care academic medical center. Fifty-one COVID-19 positive women confirmed by nasopharyngeal reverse transcription–polymerase chain reaction (RT-PCR), were compared with propensity-matched COVID negative controls (n = 51). Hemodynamic changes after neuraxial block were recorded by electronic medical recording system and analyzed using paired and unpaired T- test and Wilcoxon-Mann–Whitney Rank Sum tests. The primary outcome was ≥ 20% change in MAP and HR after neuraxial block placement. Results In the epidural group, 7% COVID-19 positive parturients had > 20% decrease in mean arterial pressure (MAP) from baseline compared to 15% COVID-19 negative parturients (P = 0.66). In the spinal group, 83% of COVID-19 positive parturients had a decrease in MAP more than 20% from baseline compared to 71% in control (P = 0.49). MAP drop of more than 40% occurred in 29% COVID positive parturients in the spinal group versus 17% in COVID-19 negative parturients (P = 0.5465). In COVID-19 positive spinal group, 54% required vasopressors whereas 38% in COVID-19 negative spinal group required vasopressors (P = 0.387). We found a significant correlation between body mass index (BMI) > 30 and hypotension in COVID ( +) parturient with odds ratio (8.63; 95% CI-1.93 – 37.21) (P = 0.007). Conclusion Incidence and severity of hypotension after neuraxial blocks were similar between COVID-19 positive and COVID-19 negative parturients. BMI > 30 was a significant risk factor for hypotension as described in preexisting literature, this correlation was seen in COVID-19 positive parturients. The likely reason for parturients with BMI > 30 in COVID negative patients not showing similar correlation, is that the sample size was small.

show abstract

Section: Introductionmentioning

confidence: 99%