Experience in Endoscopic Laser Surgery of Malignant Tumours of the Upper Aero-Digestive Tract

Steiner, Wolfgang

doi:10.1159/000415662

Cited by 141 publications

(176 citation statements)

References 0 publications

Supporting

Mentioning

148

Contrasting

Unclassified

Order By: Relevance

“…Studies on survival and the incidence of locoregional recurrence in patients with supraglottic cancer treated with CO 2 laser surgery have been carried out in large series by several authors. 4,6,9,10 Their results cannot be readily compared with our findings, mainly for the different composition of the study series; however, it should be noted that, in these studies, a low overall survival was found together with a relatively low number of recurrences. Therefore, a high number of deaths were due to causes independent of the tumor, consequently bearing on the number of patients who might have had a recurrence.…”

Section: Methodscontrasting

confidence: 73%

CO₂ laser treatment of supraglottic cancer

Motta

Esposito

Testa³

et al. 2004

Head & Neck

View full text Add to dashboard Cite

Background. The aim of the study was to evaluate the effectiveness of endoscopic CO 2 laser microsurgery in the management of supraglottic cancer.Methods. One hundred twenty-four patients (116 men and eight women; mean age, 59 years; range, 31 -81 years) with supraglottic cancer underwent CO 2 laser surgery (mean followup 5 years). The study patients were classified as follows: 45 patients, T1N0M0; 61 patients, T2N0M0; and 18 patients, T3N0M0. According to the staging, the following procedures were adopted: epiglottectomy, resection of aryepiglottic fold or false vocal cord in T1 patients (group A); resection of the false vocal cord and adjacent structures in T2 patients (group B); and supraglottic laryngectomy in T3 patients (group C). Statistical comparison of survival parameters was carried out with Wilcoxon test, considering p < .05 the minimum significance value.Results. Overall actuarial survival, adjusted actuarial survival, and no evidence of disease at 5 years were 91%, 97%, and 82% in group A; 88%, 94%, and 59% in group B; and 81%, 81%, and 51% in group C, respectively. The statistical analysis of survival parameters showed a significant difference in the comparison of T1 versus T2 and T2 versus T3 tumors (p < .01). Actuarial local control, actuarial nodal control, and actuarial distant metastasis control at 5 years were 82%, 82%, and 100% in T1 patients; 63%, 90%, and 98% in T2 patients; and 77%, 75%, and 93% in T3 patients. Laryngeal preservation rate was 88.6% in T1 patients, 85.4% in T2 patients, and 93.7% in T3 patients. Patients in groups A and B were discharged after 3 to 12 days, and patients in group C were discharged after 14 to 20 days.Conclusions. The results of this study show that endoscopic CO 2 laser surgery is highly effective in the treatment of T1 and T2 supraglottic cancer. In T3 cancer, the CO 2 laser should be implemented in those cases in which radical excision by endoscopic route is feasible. In 1978, Vaughan 1 first described the use of CO 2 laser in the treatment of early supraglottic cancer. In 1984, Motta et al illustrated the endoscopic surgical technique of supraglottic laryngectomy 2 and subsequently indicated the guidelines for supraglottic cancer resection with CO 2 laser, 3 which were validated and confirmed by other authors. 4 -7 The aim of this study was to evaluate the effectiveness of CO 2 laser microsurgery in the management of supraglottic cancer.

show abstract

Section: Methodscontrasting

confidence: 73%

CO₂ laser treatment of supraglottic cancer

Motta

Esposito

Testa³

et al. 2004

Head & Neck

View full text Add to dashboard Cite

show abstract

“…In fact, the proportion of patients receiving TL has declined from 74% in 1999 to 26% in 2007 [8] and open partial laryngectomy (OPL) together with transoral laser microsurgery (TLM), have been progressively introduced for the treatment of intermediate and advanced laryngeal tumours. Since the 1970s' when Labayle and Piquet introduced supracricoid partial laryngectomy for glottic cancer treatment [9,10] and Steiner commenced TLM for laryngeal carcinomas in 1979 [11], laryngeal preservation procedures have paved the pathway for the contemporary management of laryngeal cancer. However, whereas chemoradiation therapy protocols have a tough scientific basis [12][13][14], indications for conservative surgery still wait for full validation.…”

Section: Introductionmentioning

confidence: 99%

Conservative treatment for advanced T3–T4 laryngeal cancer: meta-analysis of key oncological outcomes

Mannelli

Lazio

Luparello

et al. 2017

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

show abstract

“…Building on these results Steiner developed new endoscopes, instruments and new techniques to handle the larynx and improve oncologic effectiveness [14]. Between 1979 and 1986 he treated almost 900 patients aged 15 -91 including over 500 patients with laryngeal carcinoma.…”

Section: The Use Of Laser On Patient's Laryngesmentioning

confidence: 99%

“…And also now with laser the possibility of treating advanced tumours with or without radiotherapy while preserving functionally important organs without the need for tracheostomy. However in whenever the carcinoma has spread beyond the larynx or into arytenoids the use of laser is very limited [14]. A more recent study on laser treatment presented by Wolfgang Steiner, MD, in 2005 showed that of 333 patients with T1a tumors, 89.3% had their lesions controlled after five years, and 97.6% of those had their larynx preserved [15].…”

Section: The Use Of Laser On Patient's Laryngesmentioning

confidence: 99%

The Evolution of Laser in Laryngology

Tahir¹

2015

IJOHNS

View full text Add to dashboard Cite

Technological breakthroughs in physics are often adapted and incorporated into the ever growing field of otolaryngology. When first discovered, "The Incredible Laser" had promised to be science's new "Aladdin's lamp", it can "light up the moon", "kill instantly", or "perform miracle surgery" [1]. Although not quite fulfilling these roles, laser technology has been a key element in the development of endolaryngeal surgery. This article looks at the invention of Laser and it's progression into an invaluable tool in the field of laryngeal surgery.

show abstract

Experience in Endoscopic Laser Surgery of Malignant Tumours of the Upper Aero-Digestive Tract

Cited by 141 publications

References 0 publications

CO₂ laser treatment of supraglottic cancer

CO₂ laser treatment of supraglottic cancer

Conservative treatment for advanced T3–T4 laryngeal cancer: meta-analysis of key oncological outcomes

The Evolution of Laser in Laryngology

Contact Info

Product

Resources

About

Experience in Endoscopic Laser Surgery of Malignant Tumours of the Upper Aero-Digestive Tract

Cited by 141 publications

References 0 publications

CO2 laser treatment of supraglottic cancer

CO2 laser treatment of supraglottic cancer

Conservative treatment for advanced T3–T4 laryngeal cancer: meta-analysis of key oncological outcomes

The Evolution of Laser in Laryngology

Contact Info

Product

Resources

About

CO₂ laser treatment of supraglottic cancer

CO₂ laser treatment of supraglottic cancer