Expeditious synthesis and cytotoxic activity of new cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines

Solvatochromic study of three indoloquinoline derivatives: Effect of chloro group/s on the photophysics of thecompounds

“…Besson et al [10][11][12] applied 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) to the synthesis of polyheterocyclic systems of potential pharmacological value and discovered that condensation of 2-(2-aminophenyl)indole and Appel salt leads to new 6-cyanoindolo [3,2-c]quinoline derivatives which are related to cryptosanguinolentine. They explored the cytotoxicity effects of these derivatives.…”

Identification of benzofuro[2,3- b ]quinoline derivatives as a new class of antituberculosis agents

“…The indoloquinoline skeleton is present in a number of natural alkaloids with broad biological effects including antibacterial, antihyperglycemic, antiinflammatory, and antimalarial activities [14][15][16][17][18]. Currently there is considerable interest in the synthesis of indoloquinoline derivatives, because of their potential biological activities [19][20][21][22][23][24][25][26][27]. However, the isomeric benzofuroquinoline derivatives have attracted only limited attention [28][29][30][31][32].…”

Synthesis of Cinnamic Acid Derivatives

“…In a word, quinoline is a dominant skeleton structure, as a supporting structure, connecting different properties of the pharmacological groups, with a variety of biological macromolecules, resulting in a variety of biological activity, especially in the field of anti-tumor drug research, quinoline Class played an important role [9]. In addition, as early as 2000, Lamazz [11] synthesized benzimidazole and quinoline compounds on human HT-29 cell inhibitory activity reached a level of micro-mol.…”