Expectant management of PPROM and major complications before planned delivery: A retrospective cohort study

Bendix, Jane M.; Hegaard, Hanne Kristine; Bergholt, Thomas; Langhoff‐Roos, Jens

doi:10.3109/01443615.2014.987114

Cited by 16 publications

(13 citation statements)

References 17 publications

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“…Almost half of all women affected by PPROM will deliver within the first 72 hours, and the risk of a major complication associated with PPROM is greatest during this time . The results of the present study suggest that after this initial high‐risk period, among women who meet specific criteria, there are no differences in adverse maternal or neonatal outcomes between those who receive PCAH and those who receive in‐hospital surveillance.…”

Section: Discussionmentioning

confidence: 61%

A retrospective cohort study of hospital versus home care for pregnant women with preterm prelabor rupture of membranes

Palmer

Grabowska

Burrows

et al. 2017

Int J Gynecol Obstet

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Section: Discussionmentioning

confidence: 61%

A retrospective cohort study of hospital versus home care for pregnant women with preterm prelabor rupture of membranes

Palmer

Grabowska

Burrows

et al. 2017

Int J Gynecol Obstet

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“…6 As balancing the risk of chorioamnionitis and neonatal complications related to prematurity is challenging for the physicians, predicting neonatal outcome is one of the key points in the appropriate management of pregnancies complicated by PPROM. 7,8 Although gestational age at delivery is the main determinant of neonatal outcomes, exposure of the fetus to the excessive intrauterine infection/inflammation was another important risk factor for neonatal complications. [9][10][11][12] Thus, estimating maternal and fetal inflammation seems to be reasonable in order to assess the prognosis of the neonate.…”

Section: Introductionmentioning

confidence: 99%

A cut‐off value for systemic immune‐inflammation index in the prediction of adverse neonatal outcomes in preterm premature rupture of the membranes

Uyanık

Ünal

Beksaç

2020

J of Obstet and Gynaecol

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Aim To determine a cut‐off value for systemic immune‐inflammation index (SII)(neutrophil × platelet /lymphocyte) in the prediction of adverse neonatal outcomes in preterm premature rupture of the membranes (PPROM). Methods This retrospective cohort study was conducted among singleton pregnancies with PPROM. Cases were divided into two main groups: Group 1) PPROM diagnosed at 24th–28th weeks of gestation and Group 2) PPROM diagnosed at >28th–34th weeks of gestation. Thereafter, main study groups were divided into two subgroups: Subgroup A: pregnancies with favorable neonatal outcomes and Subgroup B: pregnancies with composite adverse neonatal outcomes. Subgroups were compared in terms of demographic features, clinical characteristics, laboratory test results and SII values. Furthermore, cut‐off values of SII for the prediction of composite adverse neonatal outcomes were determined for two main groups. A Mann–Whitney U test was conducted to compare the median values and the chi‐square test was used to compare categorical variables among the groups. Receiver operating characteristic (ROC) curves were used to assess the performance of SII value in predicting composite adverse neonatal outcomes. Results Significant differences were observed for median platelet and SII values between the subgroups (P < 0.001 for both in group 1 and P = 0.002 and P = 0.005, respectively, in group 2). Cut‐off values of 1695.14 109/L (83.3% sensitivity, 85.7% specificity) and 1430.90 × 109/L (71.4% sensitivity, 75.7% specificity) for composite adverse neonatal outcomes were determined, respectively in group 1 and 2 according to the ROC curve analysis. Conclusion SII may be used as an additional indicator for the prediction of adverse neonatal outcomes in PPROM.

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“…This study indicates that the risks of complications are expected to be still higher in case of PPROM in less than 22 weeks of gestation [12].…”

Section: Termination Of Pregnancy Is Considered Because This Conditiomentioning

confidence: 71%

Successful Management of Preterm Premature Rupture of Membrane in Second Trimester: A Case Report and Literature Review

Jha¹,

Xiao²,

Zhang³

et al. 2019

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The preterm premature rupture of membranes occurring in early pregnancy at less than 23-24 weeks (prior to fetal viability), has higher risk for early preterm delivery, and therefore, the poorer the prognosis with poor chance of neonatal survival and a high rate of severe, long-term neonatal morbidity among survivors. In such cases in absence of overt evidence of intrauterine infection at the time of diagnosis termination of pregnancy or expectant management is generally offered modality of treatment, the prior being commonly preffered. When expectant management is instituted, it is very rare that spontaneous resealing of the membranes occurs with the outcome that is equivocal to normal pregnancy. The presented case is an example of this rare happening. A 25-year-old, mangolian, primigravida at 20 weeks of pregnancy had spontaneous preterm premature rupture of membranes. After 8 days of expectant management, she had cessation of amniotic fluid leak and could continue pregnancy till term with normal feto-maternal outcome at 37 weeks of pregnancy. The risk of infection increases with prolongation of latency period but in this case, the latency period was prolonged for more than 16 weeks and there was no evidence of infection, with normal feto-maternal outcome at term. This is the first case of its kind happened in our hospital and deserves to be reported. It is expected that this article will reveal the possibility of resealing of spontaneous preterm premature rupture of membrane with proper expectant management.

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Expectant management of PPROM and major complications before planned delivery: A retrospective cohort study

Cited by 16 publications

References 17 publications

A retrospective cohort study of hospital versus home care for pregnant women with preterm prelabor rupture of membranes

A retrospective cohort study of hospital versus home care for pregnant women with preterm prelabor rupture of membranes

A cut‐off value for systemic immune‐inflammation index in the prediction of adverse neonatal outcomes in preterm premature rupture of the membranes

Successful Management of Preterm Premature Rupture of Membrane in Second Trimester: A Case Report and Literature Review

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