Abstract:BACKGROUND: When the coronavirus pandemic caused widespread school and business closures in March 2020, blood drives were cancelled and the supply of blood decreased suddenly in the United States (US). In response, hospital-based transfusion medicine physicians instituted policies to conserve blood and decrease blood product usage. These efforts were aided by the US Surgeon General recommendation to cancel all elective procedures. Nevertheless, the duration, severity, and impact of the pandemic on the national… Show more
“…Gniadek et al studied the impact of the cancellation of elective surgeries and procedures on the demands for blood components [11]. They found that it only led to a modest, non-significant decline in the demand for packed RBCs, platelets, and FFP units.…”
Section: Strategies To Replenish Drying Blood Storesmentioning
confidence: 99%
“…They found that it only led to a modest, non-significant decline in the demand for packed RBCs, platelets, and FFP units. To tackle this crisis, the transfusion medicine department at NorthShore University HealthSystem, Evanston, Chicago ramped up the in-house donor programs which led to a 5-fold increment in the storage for whole blood units [11]. has also requested the general public to come forward for blood donation [12].…”
Section: Strategies To Replenish Drying Blood Storesmentioning
“…Gniadek et al studied the impact of the cancellation of elective surgeries and procedures on the demands for blood components [11]. They found that it only led to a modest, non-significant decline in the demand for packed RBCs, platelets, and FFP units.…”
Section: Strategies To Replenish Drying Blood Storesmentioning
confidence: 99%
“…They found that it only led to a modest, non-significant decline in the demand for packed RBCs, platelets, and FFP units. To tackle this crisis, the transfusion medicine department at NorthShore University HealthSystem, Evanston, Chicago ramped up the in-house donor programs which led to a 5-fold increment in the storage for whole blood units [11]. has also requested the general public to come forward for blood donation [12].…”
Section: Strategies To Replenish Drying Blood Storesmentioning
“…Maintaining adequate supplies of safe blood in order to guarantee the execution of necessary surgical procedures or other medical activities can prove to be particularly difficult in emergency situations, especially epidemics. In the first few months of the pandemic, many countries [ 51 ], including Italy [ 52 ], experienced a consistent decrease in donations and, therefore, in the availability of hematic products. Although to date there is no evidence to suggest the possibility of virus transmission through blood from symptomatic individuals, the shortage is due to the greater difficulty in travel, the risks associated with congregating in donation centers, and a higher percentage of the population that is potentially infected and unable to donate.…”
The World Health Organization (WHO) declared the outbreak of the Coronavirus disease-2019 (COVID-19) infection a pandemic on 11 March 2020. As of the end of October 2020, there were 50 million cases of infection and over one million deaths recorded worldwide, over 45,000 of which occurred in Italy. In Italy, the demand for intensive care over the course of this pandemic crisis has been exceptionally high, resulting in a severe imbalance between the demand for and availability of the necessary resources. This paper focuses on elements of preventive medicine and medical treatments in emergency and non-emergency situations which, based on the international scientific literature, may prove to be useful to physicians on a behavioral level and avert professional liability problems. In order to achieve this objective, we have performed a search on MEDLINE to find published articles related to the risks associated with the pandemic that contain useful suggestions and strategies for mitigating risks and protecting the safety of the population. The results have been collocated in line with these specific study areas.
“…Reduced LOS increases bed availability and the ability to accommodate increases in patient volume. Fewer bleeding events allows for conservation of scarce blood products [18]. These positive outcomes by PERT occurred without a complete understanding of the pathophysiology of COVID-19 or evidence-based management guidelines.…”
Coronavirus disease 2019 (COVID-19) is associated with increased rates of deep vein thrombosis (DVT) and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been associated with improved outcomes. We aimed to investigate whether PERT utilization, recommendations, and outcomes for patients diagnosed with acute PE changed during the COVID-19 pandemic. This is a retrospective cohort study of all adult patients with acute PE who received care at an academic hospital system in New York City between March 1st and April 30th, 2020. These patients were compared against historic controls between March 1st and April 30th, 2019. PE severity, PERT utilization, initial management, PERT recommendations, and outcomes were compared. There were more cases of PE during the pandemic (82 vs. 59), but less PERT activations (26.8% vs. 64.4%, p < 0.001) despite similar markers of PE severity. PERT recommendations were similar before and during the pandemic; anticoagulation was most recommended (89.5% vs. 86.4%, p = 0.70). During the pandemic, those with PERT activations were more likely to be female (63.6% vs. 31.7%, p = 0.01), have a history of DVT/PE (22.7% vs. 1.7%, p = 0.01), and to be SARS-CoV-2 PCR negative (68.2% vs. 38.3% p = 0.02). PERT activation during the pandemic is associated with decreased length of stay (7.7 ± 7.7 vs. 13.2 ± 12.7 days, p = 0.02). PERT utilization decreased during the COVID-19 pandemic and its activation was associated with different biases. PERT recommendations and outcomes were similar before and during the pandemic, and led to decreased length of stay during the pandemic.
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