Expansion of dynamic working range and correction for interferences in flame atomic absorption spectrometry using flow-injection gradient ratio calibration with a single standard

Abstract

The potential usefulness of the reflective properties of microwave-induced plasma (MIP) as a gas chromatographic detector Is reported. The detector operation is based on the measurement of the change In reflected power arising from the Interaction of the analyte with an atmospheric pressure argon plasma sustained In the highly efficient TM010 resonant cavity. Microwave forward power and tangential gas flow are optimized for -pentane. The lowest microwave powers produced the best signal sensitivities. For the particular discharge tube employed, a maximum response Is obtained at approximately 1.6 L/mln. The nonlinear calibration curve obtained for n-pentane Is discussed, and Its conversion to a linearized calibration curve Is presented. Calculated detection limits for carbon and hydrogen lie In the upper nanograms of element per second range.

Flow Analysers

“…The experimental data were in agreement with those predicted by the random walk simulation model [57]. Similar findings were reported in relation to flame atomic absorption spectrometry: "the shape of the transient signal can be influenced only to a small extent by chemical or physical properties of the sample such as temperature and viscosity" [58]. Similarly, reduced dispersion with increasing temperature was observed in the determination of non-volatile nitrosamines using liquid chromatography, post-column redox reactions and voltammetric detection [59].…”

An overview of qualimetric strategies for optimisation and calibration in pharmaceutical analysis using flow injection techniques

“…With this algorithm, the entire working range of the instrument can be calibrated by using only one reference solution, thus avoiding any problems due to calibration graph curvature or instrumental drift. At the same time this algorithm also corrects for multiplicative interference effects, so that accurate results can be obtained even in the presence of interfering matrices [87].…”

Flow-injection atomic spectrometry: a new analytical technique

“…4. Although a number of methods for the calibra tion of atomic spectrometers by the application of FI procedures have been described [72], none has yet appeared to be an attractive proposition for commercial development, possibly because of the instrumental complexity involved in some of the reported procedures require extensive software development or precise control over the timing of various operations, or both: There is still a need for a simple reliable procedure for calibration and dilution. The· aim of the investigation is to examine the feasibility of a closed-loop procedure m which the dilution produced depends only on the volumes of loops involved and does not re :.…”