Expanding the Manufacturing Approaches for Gastroretentive Drug Delivery Systems with 3D Printing Technology
Imola-Rebeka Turac,
Alina Porfire,
Sonia Iurian
et al.
Abstract:Gastroretentive drug delivery systems (GRDDSs) have gained substantial attention in the last 20 years due to their ability to retain the drug in the stomach for an extended time, thus promoting an extended release and high bioavailability for a broad range of active pharmaceutical ingredients (APIs) that are pH-sensitive and/or have a narrow absorption window. The currently existing GRDDSs include floating, expanding, mucoadhesive, magnetic, raft-forming, ion-exchanging, and high-density systems. Although ther… Show more
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