Expanding the Living Donor Pool “Second Act”: Laparoscopic Donor Nephrectomy and ABO-Incompatible Kidney Transplantation Improve Donor Recruitment

Romagnoli, Jacopo; Salerno, Maria Paola; Mamode, Nizam; Calia, Rosaria; Spagnoletti, Gionata; Bianchi, Valentina; Maresca, Maddalena; Piccirillo, Nicola; Putzulu, Rossana; Piselli, Pierluca; Cola, E.; Zini, Gina; Citterio, Franco

doi:10.1016/j.transproceed.2014.11.071

Cited by 5 publications

(3 citation statements)

References 14 publications

(10 reference statements)

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“…The use of mini-invasive techniques for living donor nephrectomy is increasing in Italy as in the rest of the world, allowing for a potential expansion of the donor pool in the near future [15]. The present data from a national multicentric survey confirms a relation among centre volume, surgical approach and selection of the side of the kidney to be procured.…”

Section: Discussionsupporting

confidence: 69%

Are there any relations among transplant centre volume, surgical technique and anatomy for donor graft selection? Ten-year multicentric Italian experience on mini-invasive living donor nephrectomy

Ravaioli

Capocasale

Furian

et al. 2017

Nephrology Dialysis Transplantation

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Section: Discussionsupporting

confidence: 69%

Are there any relations among transplant centre volume, surgical technique and anatomy for donor graft selection? Ten-year multicentric Italian experience on mini-invasive living donor nephrectomy

Ravaioli

Capocasale

Furian

et al. 2017

Nephrology Dialysis Transplantation

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“…Incidence of end stage renal disease and number of kidneys available for renal transplant has always been a major medical concern. With the advent of laparoscopic donor nephrectomy, there has been increase in live donor pool over last decade ( 8 ). Laparoscopic donor nephrectomy offers low morbidity, shorter length of hospitalization, less pain medication requirements, and reduced convalescence as compared to open donor nephrectomy ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic donor nephrectomy in unusual venous anatomy – donor and recepient implications

et al. 2017

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Objectives Laparoscopic donor nephrectomy is now a commonly performed procedure in most of renal transplantation centers. However, the suitability of laparoscopy for donors with abnormal venous anatomy is still a subject of debate.Materials and methods Between August 2007 and August 2014, 243 laparoscopic donor nephrectomies were performed in our institution. All donors were evaluated with preoperative three-dimensional spiral computed tomography (CT) angiography Thirteen (5.35%) donors had a left renal vein anomaly. A retrospective analysis was performed to collect donor and recipient demographics and perioperative data.Results Four donors had a type I retroaortic vein, seven had type II retroaortic vein and a circumaortic vein was seen in three donors. The mean operative time was 114±11 minutes and mean warm ischemia time was 202±12 seconds. The mean blood loss was 52.7±18.4mL and no donor required blood transfusion. Mean recipient creatinine at the time of discharge was 1.15±0.18mg/dL, and creatinine at six months and one year follow-up was 1.12±0.13mg/dL and 1.2±0.14mg/dL, respectively. There were no significant differences in operative time, blood loss, warm ischemia time, donor hospital stay or recipient creatinine at 6 months follow-up, following laparoscopic donor nephrectomy in patients with or without left renal vein anomalies. Conclusion Preoperative delineation of venous anatomy using CT angiography is as important as arterial anatomy. Laparoscopic donor nephrectomy is safe and feasible in patients with retroaortic or circumaortic renal vein with good recipient outcome.

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“…The introduction of AB0 incompatible kidney transplant in our centre had only temporary beneficial effect in increasing the numbers of living kidney donations. We observed that the choice of the surgical technique might also play an important role for possible kidney donors before making the final decision (2).…”

Section: Introductionmentioning

confidence: 99%

Successful laparoscopic living donor nephrectomy: first experience in Lithuania

Laučytė-Cibulskienė¹,

Miglinas²,

Želvys³

et al. 2019

AML

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Background. The aim of this paper is to share the initial results of LLDN in high-volume university centre that is performing laparoscopic nephrectomies for other indications. Materials and methods. During 2017, four LLDNs were performed. The transperitoneal approach was used in all cases and the kidney was removed using a suprapubic incision. All donors and recipients were prospectively analysed within six-month follow-up. The patients’ clinical, laboratory, and operation-related data were collected from direct interviews with them and from medical records. All patients signed written informed consent. Results. One male and three females donated their left kidneys by using the LLDN technique. The mean age was 58 ± 9 years; two of them with a history of previous cholecystectomy. All donated kidneys had a single renal artery and renal vein. Pre-operative average eGFR was 94.2 ± 7.1 ml/min/1.73 m2, immediately after LLDN 57.5 ± 10.3 ml/min/1.73 m2, after one month 56.0 ± 9.1 ml/min/1.73 m2. There were no intraoperative complications; surgery duration was 223.75 ± 21.74 min, the cold ischemia time was 77.5 ± 28.77 min, and the warm ischemia time 6.37 ± 3.14 min. There was one postoperative donor complication, one case of acute kidney injury, and one case of prolonged postoperative abdominal pain. The only recipient complication was one case of acute kidney rejection; there were no cases of delayed graft function. Conclusions. Our initial experience confirms that LLDN is an approach that is easy to learn, especially in a high-volume university hospital with expertise in performing laparoscopic nephrectomies for other indications.

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Expanding the Living Donor Pool “Second Act”: Laparoscopic Donor Nephrectomy and ABO-Incompatible Kidney Transplantation Improve Donor Recruitment

Cited by 5 publications

References 14 publications

Are there any relations among transplant centre volume, surgical technique and anatomy for donor graft selection? Ten-year multicentric Italian experience on mini-invasive living donor nephrectomy

Are there any relations among transplant centre volume, surgical technique and anatomy for donor graft selection? Ten-year multicentric Italian experience on mini-invasive living donor nephrectomy

Laparoscopic donor nephrectomy in unusual venous anatomy – donor and recepient implications

Successful laparoscopic living donor nephrectomy: first experience in Lithuania

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